Human TEM5/GPR124 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB88961V Datasheet / COA / SDS

Human TEM5/GPR124 MAb (Clone 499708)

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FAB88961V-100UG

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All TEM5/GPR124 Antibodies

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Human TEM5/GPR124 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human TEM5/GPR124 in direct ELISAs.

Source

Monoclonal Mouse IgG2a Clone # 499708

Purification

Protein A or G purified

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human TEM5/GPR124
Met1-Leu699
Accession # Q96PE1

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TEM5/GPR124

G protein-coupled receptor 124 (GPR124, also known as TEM5), is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. GPR124 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. This receptor mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans. GPR124 has also been shown to interact with DLG1 through its PDZ-binding motif.

Long Name

Tumor Endothelial Marker 5

Entrez Gene IDs

25960 (Human); 78560 (Mouse)

Alternate Names

DKFZp434C211; DKFZp434J0911; G protein-coupled receptor 124; GPR124; G-protein coupled receptor 124; KIAA1531; KIAA1531FLJ14390; TEM5; TEM5Tumor endothelial marker 5