TMEM18 is an obesity risk gene. It is a small protein of 140 residues and is predicted to be mostly alpha-helical with three transmembrane parts. TMEM18 forms homooligomers, independently of the DNA-binding domain. TMEM18 localizes to the nuclear membrane and binds to DNA in a sequence-specific manner. TMEM18 is a transcription repressor sequence-specific ssDNA and dsDNA binding protein with preference for GCT end CTG repeats. TMEM18 is a cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).
Human TMEM18 (NP_690047) VersaClone cDNA
R&D Systems | Catalog # RDC0226
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: TMEM18
Long Name
Transmembrane Protein 18
Alternate Names
transmembrane protein 18
Gene Symbol
TMEM18
UniProt
Additional TMEM18 Products
Product Documents for Human TMEM18 (NP_690047) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human TMEM18 (NP_690047) VersaClone cDNA
For research use only
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