Human TSH beta Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB57941T Datasheet / COA / SDS

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FAB57941T-100UG

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Human TSH beta Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects TSH beta in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant rat TSH beta was observed.

Source

Monoclonal Mouse IgG1 Clone # 512908

Purification

Protein A or G purified

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human TSH Î²
Phe21-Val138
Accession # NP_000540

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TSH beta

TSH beta is the 138 amino acid (aa), 15 kDa unique subunit of Thyroid Stimulating Hormone (TSH), which shares a common alpha subunit with other glycoprotein hormones lutropin (LH), follitropin (FSH) and chorionic gonadotropin (CG). Production of TSH by the anterior pituitary gland is stimulated by the hypothalamic peptide TRH, and inhibited by feedback from the thyroid hormones triiodothyronine (T3) and thyroxine (T4). Mature human TSH beta shares 89% and 90% aa sequence identity with mouse and rat TSH beta, respectively.

Long Name

Thyroid-stimulating Hormone Subunit beta

Entrez Gene IDs

7252 (Human); 22094 (Mouse); 25653 (Rat)

Alternate Names

thyroid stimulating hormone, beta; thyroid-stimulating hormone subunit beta; thyrotropin beta chain; thyrotropin beta subunit; Thyrotropin beta; thyrotropin subunit beta; TSH beta; TSHB; TSH-B; TSH-BETA