Human ZBTB38 Alexa Fluor® 750-conjugated Antibody

Catalog #: AF5784S Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF5784S-100UG

All ZBTB38 Antibodies

Product Details

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human ZBTB38 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects endogenous human ZBTB38 in Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human ZBTB38
Met1-Tyr232
Accession # Q8NAP3

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ZBTB38

ZBTB38 (Zinc finger and BTB domain-containing protein 38; also CIBZ and Zenon) is an early member of a family of Kaiso-like DNA binding proteins. Although its predicted MW is 134 kDa, it runs anomalously in SDS-PAGE at 175 kDa. ZBTB38 binds to singly methylated CpG (cytosine-phosphate-guanine) motifs. It is considered a transcriptional repressor that either homodimerizes, or heterodimerizes with ZBTB4, and subsequently interacts with either CtBP-1 or -2 to mediate repression. Human ZBTB38 is 1195 amino acids (aa) in length. It contains a BTB domain (aa 33‑100), an RD2 region (aa 158‑341) and ten C2H2-type zinc finger domains (aa 342‑1147). There is one potential alternate start site at Met595. Over aa 1‑232, human ZBTB38 shares 96% aa identity with mouse ZBTB38.

Long Name

Zinc Finger and BTB Domain-Containing Protein 38

Entrez Gene IDs

253461 (Human); 245007 (Mouse); 315936 (Rat)

Alternate Names

CIBZ; FLJ22332; FLJ31131; FLJ35036; STQTL10; ZBTB38; zinc finger and BTB domain containing 38; zinc finger and BTB domain-containing protein 38; ZNF921