HYPB Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-89843

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (94%), Rat (92%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all HYPB Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVA

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 25728682).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HYPB Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: HYPB Antibody [NBP1-89843]

Immunocytochemistry/ Immunofluorescence: HYPB Antibody [NBP1-89843]

Immunocytochemistry/Immunofluorescence: HYPB Antibody [NBP1-89843] - Immunofluorescent staining of human cell line A-431 shows localization to nuclear speckles & cytosol.
Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843] - Staining of human small intestine shows strong nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843] - Staining of human endometrium shows strong nuclear positivity in glandular and stromal cells.
Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843] - Staining of human testis shows moderate nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843]

Immunohistochemistry-Paraffin: HYPB Antibody [NBP1-89843] - Staining of human cerebellum shows moderate nuclear positivity in Purkinje cells as well as in cells in molecular layer.

Applications for HYPB Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HYPB

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. (provided by RefSeq)

Alternate Names

FLJ22472, FLJ23184, FLJ45883, FLJ46217, HIF1, HIF-1EC 2.1.1.43, HIP-1, histone-lysine N-methyltransferase SETD2, hSET2, huntingtin interacting protein 1, Huntingtin yeast partner B, Huntingtin-interacting protein 1, Huntingtin-interacting protein B, HYPBp231HBP, KIAA1732SET domain-containing protein 2, KMT3AHBP231, Lysine N-methyltransferase 3A, SET domain containing 2, SET2FLJ16420

Gene Symbol

SETD2

Additional HYPB Products

Product Documents for HYPB Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for HYPB Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for HYPB Antibody - BSA Free

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Protocols

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FAQs

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