ICOS Antibody (CL14825) - Azide and BSA Free

Novus Biologicals | Catalog # NBP3-44351

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL14825

Format

Azide and BSA Free
View all ICOS Primary Antibodies »

Product Specifications

Immunogen

This antibody was generated using a synthetic peptide of Q9Y6W8, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for ICOS Antibody (CL14825) - Azide and BSA Free

ICOS Antibody (CL14825) - Azide and BSA Free Western Blot: ICOS Antibody [NBP3-44351]

Western Blot: ICOS Antibody [NBP3-44351]

Analysis in human cell line MOLT-4.

Applications for ICOS Antibody (CL14825) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: ICOS

The C398.4A antibody reacts with the human, mouse and rat 47-57 kD ICOS protein, also known as inducible costimulatory molecule and H4. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS is involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7h/B7RP-1 or B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development. The C398.4A antibody is useful for flow cytometric analysis and is able to costimulate T cell activation and proliferation.

Long Name

Inducible Co-stimulator

Alternate Names

AILIM, CD278, CRP-1

Gene Symbol

ICOS

Additional ICOS Products

Product Documents for ICOS Antibody (CL14825) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for ICOS Antibody (CL14825) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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