IL-13R alpha 1 Antibody (5A3W5)

Name: IL-13R alpha 1 Antibody (5A3W5)
Brand: Novus Biologicals
SKU: NBP3-16207
Price: 399 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-16207

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 5A3W5 expressed in HEK293

View all IL-13 R alpha 1 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IL-13R alpha 1 (P78552). MEWPARLCGLWALLLCAGGGGGGGGAAPTETQPPVTNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERICLQVGS

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-13R alpha 1 Antibody (5A3W5)

Western Blot: IL-13R alpha 1 Antibody (5A3W5) [NBP3-16207]

Western Blot: IL-13R alpha 1 Antibody (5A3W5) [NBP3-16207] - Western blot analysis of extracts of various cell lines, using IL-13R alpha 1 antibody (NBP3-16207) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Immunohistochemistry-Paraffin: IL-13R alpha 1 Antibody (5A3W5) [NBP3-16207]

Immunohistochemistry-Paraffin: IL-13R alpha 1 Antibody (5A3W5) [NBP3-16207] - Immunohistochemistry of paraffin-embedded human lung cancer using IL-13R alpha 1 Rabbit mAb (NBP3-16207) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Applications for IL-13R alpha 1 Antibody (5A3W5)

Application

Recommended Usage

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IL-13 R alpha 1

IL13 receptor alpha 1 is encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alph,a a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

Long Name

Interleukin 13 Receptor alpha 1

Alternate Names

CD213a1, IL-13Ra1, IL13R alpha 1, IL13RA1

Gene Symbol

IL13RA1

Additional IL-13 R alpha 1 Products

Product Documents for IL-13R alpha 1 Antibody (5A3W5)

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Certificate of Analysis

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Product Specific Notices for IL-13R alpha 1 Antibody (5A3W5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.