Interleukin 36 beta (IL-36 beta), also known as IL-1F8, FIL-1h and IL-1H2, is a member of the IL-1 family of proteins. IL-36 beta is reported to be actively secreted. Cells expressing IL-36 beta include resting and activated monocytes, and B cells. The receptor for IL-36 beta is thought to be a combination of IL-1 Rrp2 and IL-1 RAcP. Recombinant IL-36 beta activates pathways involving NF-kB and MAPK in an IL-1 Rrp2-dependent manner.
IL-36 beta/IL-1F8 Antibody (Jacky-1) [Biotin]
Novus Biologicals | Catalog # NBP2-80085B
Key Product Details
Species Reactivity
Human
Applications
Western Blot, ELISA
Label
Biotin
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # Jacky-1
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Product Specifications
Immunogen
Recombinant human IL-36 beta/IL-1F8.
Specificity
Recognizes human IL-36 beta/IL-1F8. Does not cross-react with mouse IL-36 beta/IL-1F8 and IL-36gamma.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for IL-36 beta/IL-1F8 Antibody (Jacky-1) [Biotin]
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: IL-36 beta/IL-1F8
Long Name
Interleukin 36 beta/Interleukin 1 Family 8
Alternate Names
FIL1 eta, IL-1 eta, IL-1H2, IL1F8, IL36 beta, IL36B
Gene Symbol
IL36B
Additional IL-36 beta/IL-1F8 Products
Product Documents for IL-36 beta/IL-1F8 Antibody (Jacky-1) [Biotin]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for IL-36 beta/IL-1F8 Antibody (Jacky-1) [Biotin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
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- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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Associated Pathways
