IL-3R alpha/CD123 Antibody Pair [HRP]

Name: IL-3R alpha/CD123 Antibody Pair [HRP]
Brand: Novus Biologicals
SKU: NBP2-79483
Price: 349 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-79483

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Product Specifications
Scientific Data
Kit Contents
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Assay Type

Sandwich ELISA

Assay Range

31.25-2000 pg/ml (example only; lot dependent)

Sensitivity

31.25 pg/ml (example only; lot dependent)

Reactivity

Human

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Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Human IL-3R alpha/CD123.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for IL-3R alpha/CD123 Antibody Pair [HRP]

Sandwich ELISA: IL-3R alpha/CD123 Antibody Pair [HRP] [NBP2-79483] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for IL-3R alpha/CD123 Antibody Pair [HRP]

Mouse Monoclonal Capture Antibody
Rabbit Monoclonal Detection Antibody (HRP-conjugated): (Catalog # NBP2-89549)
Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: IL-3R alpha

IL3RA (CD123) is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind IL3 with low affinity but cannot transduce signals without association with additional protein partners. CD123 can complex with either common beta chain (CDw131) or the IL3RB chain to form high affinity heterodimeric IL3 receptors. CDw131 can complex with the Alpha subunits of the mouse IL3R, IL5R and GMCSFR to form high affinity receptors, while the IL3RB subunit is specific for IL3 but binds with low affinity. IL3 binding to the receptor complex can induce proliferation and differentiation of hematopoietic cells. It is present in Hematopoietic progenitors, basophils, mast cells and megakaryocytes.

Long Name

Interleukin 3 Receptor alpha

Alternate Names

CD123, IL-3 R alpha, IL-3Ra, IL3R alpha, IL3RA

Gene Symbol

IL3RA

Additional IL-3R alpha Products

Product Documents for IL-3R alpha/CD123 Antibody Pair [HRP]

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Download Manual - IL-3R alpha/CD123 Antibody Pair [HRP]

Certificate of Analysis

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Product Specific Notices for IL-3R alpha/CD123 Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.