IL-3R alpha/CD123 Antibody

Name: IL-3R alpha/CD123 Antibody
Brand: Novus Biologicals
SKU: NBP2-27160
Price: 139 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-27160

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

A portion of amino acids120-170 of human IL-3 R alpha/CD123 was used as the immunogen for this antibody.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-3R alpha/CD123 Antibody

Western Blot: IL-3R alpha/CD123 Antibody [NBP2-27160]

Western Blot: IL-3 R alpha/CD123 Antibody [NBP2-27160] - Analysis of IL-3Ra (CD123) in A431 cell lysate in the (1) absence and (2) presence of immunizing peptide using IL-3Ra antibody at 5 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for IL-3R alpha/CD123 Antibody

Application

Recommended Usage

Western Blot

3-5ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IL-3R alpha

IL-3Ra(Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. It is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. It is also reported thatIL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.

Long Name

Interleukin 3 Receptor alpha

Alternate Names

CD123, IL-3 R alpha, IL-3Ra, IL3R alpha, IL3RA

Gene Symbol

IL3RA

UniProt

P26951

Additional IL-3R alpha Products

Product Documents for IL-3R alpha/CD123 Antibody

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Certificate of Analysis

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Product Specific Notices for IL-3R alpha/CD123 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.