Integrin beta-like protein 1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-82473

Novus Biologicals
Loading...

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Predicted:

Mouse (92%), Rat (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
Loading...

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Integrin beta-like protein 1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473]

Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473]

Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473] - Staining of human colorectal cancer shows moderate positivity.
Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473]

Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473]

Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473] - Staining of human lung shows strong cytoplasmic positivity in macrophages.
Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473]

Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473]

Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473]

Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473]

Immunohistochemistry-Paraffin: Integrin beta-like protein 1 Antibody [NBP1-82473] - Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts.
Integrin beta-like protein 1 Antibody - BSA Free

Immunohistochemistry: Integrin beta-like protein 1 Antibody - BSA Free [NBP1-82473] -

ITGBL1 expression is upregulated in HCC tissues and associated with the prognosis of HCC patients. A, ITGBL1 expression in the normal liver tissues (n = 50) and primary liver tumour tissues (n = 371), as revealed by the TCGA HCC data set (P <.001). B, ITGBL1 expression in the normal liver (n = 19) and HCC tissues (n = 47), as revealed by the Oncomine database (GSE14323; P <.001). C, Different ITGBL1 mRNA expression levels in 22 paired samples of HCC tumour tissues and adjacent non‐cancerous tissues, as determined by RT‐PCR analyses (P =.0057). D, Western blotting analyses of the ITGBL1 protein expression levels in eight randomly selected tumour tissues and the matched adjacent non‐tumour tissues from HCC patients; GAPDH was used as the internal loading control. E, Greyscale analysis of the ITGBL1 expression level, compared to the GAPDH expression level, in the eight patients (P <.001). T, tumour tissue; N, normal tissue. F, Immunochemistry staining of ITGBL1 in the TMAs with HCC tissues and adjacent non‐cancerous tissues (n = 98; P <.001). G, The Kaplan‐Meier plot for the overall survival of HCC patients according to ITGBL1 expression levels (higher vs lower, log‐rank test, P =.014) Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/32537856), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Applications for Integrin beta-like protein 1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ITGBL1

Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.

Long Name

Integrin beta-like 1

Alternate Names

Integrin beta-like 1, OSCP, TIED

Gene Symbol

ITGBL1

Additional ITGBL1 Products

Product Documents for Integrin beta-like protein 1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Integrin beta-like protein 1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Integrin beta-like protein 1 Antibody - BSA Free

Customer Reviews for Integrin beta-like protein 1 Antibody - BSA Free

There are currently no reviews for this product. Be the first to review Integrin beta-like protein 1 Antibody - BSA Free and earn rewards!

Have you used Integrin beta-like protein 1 Antibody - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies
Loading...