Ionomycin calcium salt

  ( 10 citations )    
Product Datasheet
Catalog Number:1704
Chemical Name:(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid calcium salt
Product Details
Citations (10)
Reviews
Biological Activity
Calcium ionophore; more specific than A23187.

Free Acid also available.

Technical Data
  • M.Wt:
    747.08
  • Formula:
    C41H70O9.Ca
  • Solubility:
    Soluble to 100 mM in ethanol and to 25 mM in DMSO with gentle warming
  • Purity:
    >98
  • Storage:
    Desiccate at -20°C
  • CAS No:
    56092-82-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Ionomycin calcium salt include:

10 Citations: Showing 1 - 10
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  1. Hypotonic stress induces RANKL via transient receptor potential melastatin 3 (TRPM3) and vaniloid 4 (TRPV4) in human PDL cells.
    Authors: Son Et al.
    J Dent Res  2015;94:473
  2. Binding of αherpesvirus Glycoprotein H to Surface α4β1-Integrins Activates Calcium-Signaling Pathways and Induces Phosphatidylserine Exposure on the Plasma Membrane.
    Authors: Azab Et al.
    PLoS One  2015;6
  3. Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype.
    Authors: Plog Et al.
    PLoS One  2015;10:e0140050
  4. Assessment of TTX-s and TTX-r Action Potential Conduction along Neurites of NGF and GDNF Cultured Porcine DRG Somata.
    Authors: Jonas Et al.
    J Pharmacol Exp Ther  2015;10:e0139107
  5. TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis.
    Authors: Shambharkar Et al.
    MBio  2015;10:e0127480
  6. Activation of ERK1/2 by store-operated calcium entry in rat parotid acinar cells.
    Authors: Soltoff and Lannon
    PLoS One  2013;8:e72881
  7. Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B.
    Authors: Barcomb Et al.
    Mol Pharmacol  2013;84:834
  8. Evidence that Ca2+ within the microdomain of the L-type voltage gated Ca2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1.
    Authors: Selway Et al.
    PLoS One  2012;7:e33004
  9. TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity.
    Authors: Shahidullah Et al.
    Am J Physiol Cell Physiol  2012;302:C1751
  10. Involvement of dominant-negative spliced variants of the intermediate conductance Ca2+-activated K+ channel, K(Ca)3.1, in immune function of lymphoid cells.
    Authors: Ohya Et al.
    J Biol Chem  2011;286:16940

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