Ionomycin free acid
Chemical Name: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
Biological ActivityIonomycin free acid is a calcium ionophore; more specific than A23187.
Calcium Salt also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Characterization of ionomycin as a calcium ionophore.
Liu and Hermann
Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria.
Kaufmann et al.
Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils.
Elzi et al.
Am.J.Physiol.Cell Physiol., 2001;281:C350
Citation for Ionomycin free acid
The citations listed below are publications that use Tocris products. Selected citations for Ionomycin free acid include:
1 Citation: Showing 1 - 1
Manipulation of Gut Microbiota Influences Immune Responses, Axon Preservation, and Motor Disability in a Model of Progressive Multiple Sclerosis.
Authors: Mestre Et al.
Front Immunol 2019;10:1374
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