Ionomycin free acid

Catalog # Availability Size / Price Qty
2092/1
Calcium Signaling Agents Small Molecule
1 Image
Description: Calcium ionophore

Chemical Name: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid

Product Details
Reviews (1)

Biological Activity

Calcium ionophore; more specific than A23187.

Calcium Salt also available.

Technical Data

M.Wt:
709.01
Formula:
C41H72O9
Solubility:
Soluble to 10 mM in ethanol and to 10 mM in DMSO
Storage:
Desiccate at -20°C
CAS No:
56092-81-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Ionomycin increases flow of extracellular Ca2+ Into cells leading to increased T-cell activation by IFNg
By Li Zhu on 01/23/2019
Species: Human

Ionomycin was used as a calcium ionophore to bring large amounts of extracellular Ca2+ into activated CD8+ T-cells. With high intracellular Ca2+, this led to increased activation of CD8+ T-cells as measured by IFNg production via intracellular flow cytometry.


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