Catalog Number: 2092
Chemical Name: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
Biological Activity
Calcium ionophore; more specific than A23187 (Cat. No. 1234).
Technical Data
  • M.Wt:
    709.01
  • Formula:
    C41H72O9
  • Solubility:
    Soluble to 10 mM in ethanol and to 10 mM in DMSO
  • Storage:
    Desiccate at -20°C
  • CAS No:
    56092-81-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Characterization of ionomycin as a calcium ionophore.
    Liu and Hermann
    J.Biol.Chem., 1978;253:5892
  2. Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria.
    Kaufmann et al.
    J.Biol.Chem., 1980;255:2735
  3. Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils.
    Elzi et al.
    Am.J.Physiol.Cell Physiol., 2001;281:C350

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