ISG15 Activating Enzyme/UBE1L Antibody (SR4330) - BSA Free

Novus Biologicals | Catalog # NBP3-27849

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR4330 expressed in HEK293

Format

BSA Free
View all ISG15 Activating Enzyme/UBE1L Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human ISG15 Activating Enzyme/UBE1L (Uniprot #: P41226)

Specificity

Detects endogenous levels of total ISG15 Activating Enzyme/UBE1L

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

112 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ISG15 Activating Enzyme/UBE1L Antibody (SR4330) - BSA Free

Western Blot: ISG15 Activating Enzyme/UBE1L Antibody (SR4330) [NBP3-27849] -

Western Blot: ISG15 Activating Enzyme/UBE1L Antibody (SR4330) [NBP3-27849] - Western blot analysis of HepG2 cell lysate.

Applications for ISG15 Activating Enzyme/UBE1L Antibody (SR4330) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:50

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ISG15 Activating Enzyme/UBE1L

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

Alternate Names

D8, UBA1B, UBA7, UBE2

Gene Symbol

UBA7

Additional ISG15 Activating Enzyme/UBE1L Products

Product Documents for ISG15 Activating Enzyme/UBE1L Antibody (SR4330) - BSA Free

Certificate of Analysis

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Product Specific Notices for ISG15 Activating Enzyme/UBE1L Antibody (SR4330) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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