JAM-A Antibody (RM275)

Name: JAM-A Antibody (RM275)
Brand: Novus Biologicals
SKU: NBP2-61562
Price: 439 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-61562

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM275 expressed in HEK293

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Product Specifications

Immunogen

A peptide corresponding to the N-terminus of Human JAM-A

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for JAM-A Antibody (RM275)

Western Blot: JAM-A Antibody (RM275) [NBP2-61562]

Western Blot: JAM-A Antibody (RM275) [NBP2-61562] - Western Blot of HEK293 cells lysates using NBP2-61562.

Immunohistochemistry-Paraffin: JAM-A Antibody (RM275) [NBP2-61562]

Immunohistochemistry-Paraffin: JAM-A Antibody (RM275) [NBP2-61562] - Immunohistochemical staining of formalin fixed and paraffin embedded Human kidney tissue sections using NBP2-61562.

Applications for JAM-A Antibody (RM275)

Application

Recommended Usage

Immunohistochemistry

1:2000 - 1:10000

Immunohistochemistry-Paraffin

1:2000-1:10000

Western Blot

1:250-1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: JAM-A

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Long Name

Junctional Adhesion Molecule A

Alternate Names

CD321, F11R, JAMA, PAM-1

Gene Symbol

F11R

Additional JAM-A Products

Product Documents for JAM-A Antibody (RM275)

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Certificate of Analysis

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Product Specific Notices for JAM-A Antibody (RM275)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.