Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all KOR Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide comprising residues 366-380 of the human KOR-1 protein. Sequence identity is 66% in mouse and rat.

Reactivity Notes

Human and rat.

Specificity

Kappa Opioid Receptor

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit KOR Antibody - BSA Free (NB110-79876) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for KOR Antibody - BSA Free

Western Blot: KOR AntibodyBSA Free [NB110-79876]

Western Blot: KOR AntibodyBSA Free [NB110-79876]

Western Blot: Kappa Opioid Receptor Antibody [NB110-79876] - WB detection of Kappa Opioid Receptor / KOR-1 in 10 ug of human brain lysate (lane 1) and rat brain lysate (lane 2) with this antibody at a dilution of 1:500.

Applications for KOR Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:100-1:2000
Application Notes
Western Blot

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KOR

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors that activate intracellular signaling cascades and undergo endocytosis, recycling, or degradation upon stimulation. The (mu), delta and kappa opioid receptors are GPCRs of the nervous system, which control pain, stress, and addictive behaviors. The kappa opioid receptor (KOR-1) plays a role in arousal and regulation of autonomic and neuroendocrine functions and is the receptor for dynorphins. KOR-1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Long Name

Kappa Opioid Receptor

Alternate Names

OPRK1, Oprk2, R21

Entrez Gene IDs

4986 (Human); 29335 (Rat)

Gene Symbol

OPRK1

Additional KOR Products

Product Documents for KOR Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for KOR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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