149 results for "KOR" in Products
KOR Products
Kappa Opioid Receptor (KOR) is a 45 kDa 7TM opioid receptor that is primarily expressed in the central nervous system and peripheral visceral pain sensory nerves. Following ligation by dynorphin peptides, KOR signaling induces analgesia, dysphoria, diuresis, and increased feeding desire. KOR also exerts neuroprotective and anti-inflammatory effects. Human KOR shares 94% amino acid sequence identity with mouse and rat KOR.
Selective κ agonist
| Chemical Name: | trans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride |
| Purity: | ≥99% |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #387301 |
| Applications: | Flow, ICC/IF, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #387310 |
| Applications: | IHC |
Selective κ agonist; more active enantiomer of (±)-U-50488 (Cat. No. 0495)
| Chemical Name: | trans-(-)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride |
| Purity: | ≥99% |
Endogenous κ agonist
| Purity: | ≥95% |
Activator of κ-opioid DREADD (KORD)
| Chemical Name: | (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-Furanyl)dodecahydro-9-hydroxy-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester |
| Purity: | ≥98% |
Opioid receptor antagonist
| Chemical Name: | (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol hydrochloride |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody.
| Reactivity: | Rat |
| Details: | Rabbit IgG Monoclonal Clone #1123A |
| Applications: | ICC/IF |
Selective κ agonist; less active enantiomer of (±)-U-50488 (Cat. No. 0495)
| Chemical Name: | trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride |
| Purity: | ≥99% |
Selective and irreversible κ antagonist
| Chemical Name: | 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride |
| Purity: | ≥98% |
κ agonist, acts peripherally
| Chemical Name: | (RS)-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl]phenoxy]acetic acid hydrochloride |
| Purity: | ≥98% |
Subtype-selective κ agonist
| Chemical Name: | 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate |
| Purity: | ≥99% |
Selective κ opioid receptor antagonist
| Chemical Name: | N-[3-[4-(4-Methoxyphenyl)-1-piperazinyl]propyl]-1-methyl-6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazine-5(6H)-acetamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: KOR Antibody [NBP1-68860]](https://resources.rndsystems.com/images/products/KOR-Antibody-Western-Blot-NBP1-68860-img0003.jpg "Western Blot: KOR Antibody [NBP1-68860]")
| Reactivity: | Human |
| Reactivity: | Rat |
| Reactivity: | Human, Rat, Canine, Equine, Monkey, +1 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: KOR Antibody - BSA Free [NLS228]](https://resources.rndsystems.com/images/products/KOR-Antibody-Immunohistochemistry-Paraffin-NLS228-img0002.jpg "Immunohistochemistry-Paraffin: KOR Antibody - BSA Free [NLS228]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: KOR Antibody [NBP2-68859]](https://resources.rndsystems.com/images/products/KOR-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-68859-img0001.jpg "Immunocytochemistry/ Immunofluorescence: KOR Antibody [NBP2-68859]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #387310 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #387310 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #387310 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #387310 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #387310 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #387310 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #387310 |
| Applications: | IHC |