L1CAM Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-86544

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all L1CAM Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATE

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 25862471).

Marker

Axon Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for L1CAM Antibody - BSA Free

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544] - Staining in human cerebral cortex and skeletal muscle tissues.. Corresponding L1CAM RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuropil.
Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544] - Staining of human kidney shows moderate membranous positivity in cells in distal tubules.
Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544]

Immunohistochemistry-Paraffin: L1CAM Antibody [NBP1-86544] - Staining of human colon shows moderate positivity in peripheral nerve / ganglion.

Applications for L1CAM Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: L1CAM

The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.

Long Name

Cell Adhesion Molecule L1

Alternate Names

CAML1, CD171, HSAS, HSAS1, MASA, MIC5, NCAM-L1, S10, SPG1

Gene Symbol

L1CAM

Additional L1CAM Products

Product Documents for L1CAM Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for L1CAM Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for L1CAM Antibody - BSA Free

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Protocols

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FAQs

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