Latanoprost

Catalog # Availability Size / Price Qty
4757/10
Latanoprost | CAS No. 130209-82-4 | Prostanoid Receptor Agonists
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Description: FP prostaglandin receptor agonist; also exhibits agonist activity at EP1 and EP3 receptors

Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptanoic acid 1-methylethyl ester

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Biological Activity

FP prostaglandin receptor agonist; displays greater selectivity than prostanglandin F2α (Cat. No. 4214). Exhibits agonist activity at EP1 and EP3 receptors, but little-to-no effect at EP2, DP, IP and TP prostanoid receptors.

Technical Data

Formula:
C26H40O5
Solubility:
Soluble to 50 mM in DMSO and to 50 mM in ethanol
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
130209-82-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. From PGF2α-isopropyl ester to latanoprost: a review of the development of xalatan: the Proctor Lecture.
    Stjernschantz
    Invest.Ophthalmol.Vis.Sci., 2001;42:1134

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