Lubricin/PRG4 Antibody

Novus Biologicals | Catalog # NB100-74453

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all Lubricin/PRG4 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues C L(1356) P N I R K Q P D G Y D Y Y A F S K D Q(1374) of human Lubricin.

Localization

Secreted

Specificity

Detects Lubricin in human samples.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Lubricin/PRG4 Antibody

Western Blot: Lubricin/PRG4 Antibody [NB100-74453]

Western Blot: Lubricin/PRG4 Antibody [NB100-74453]

Western Blot: Proteoglycan 4 Antibody [NB100-74453] - Analysis of 3ug of non-reduced human synovial fluid per well onto a SDS-PAGE gel.
Western Blot: Lubricin/PRG4 Antibody [NB100-74453]

Western Blot: Lubricin/PRG4 Antibody [NB100-74453]

Western Blot: Proteoglycan 4 Antibody [NB100-74453] - Analysis of Human recombinant Lubricin.

Applications for Lubricin/PRG4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Western Blot

2 ug/ml

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Lubricin/PRG4

Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.

Long Name

Proteoglycan 4

Alternate Names

CACP, HAPO, Hemangiopoietin, JCAP, MSF, PRG4, Proteoglycan 4, SZP

Entrez Gene IDs

10216 (Human)

Gene Symbol

PRG4

Additional Lubricin/PRG4 Products

Product Documents for Lubricin/PRG4 Antibody

Certificate of Analysis

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Product Specific Notices for Lubricin/PRG4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Proteoglycans

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Protocols

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FAQs

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