Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)

Novus Biologicals | Catalog # NBP3-51788

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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 24GB6730
View all Lymphotoxin beta R/TNFRSF3 Primary Antibodies »

Product Specifications

Immunogen

Recombinant protein of human Lymphotoxin beta R/TNFRSF3 (Uniprot: P36941)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Scientific Data Images for Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)

Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)

Immunocytochemistry/ Immunofluorescence: Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)[NBP3-51788] -

Immunocytochemical staining of HepG2 cells with Lymphotoxin beta R/TNFRSF3 antibody (1:1,000). Nuclei were stained blue with DAPI; Lymphotoxin beta R/TNFRSF3 was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Low. Scale bar, 20 um.
Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)

Western Blot: Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)[NBP3-51788] -

Western blotting analysis using Lymphotoxin beta R/TNFRSF3 antibody (1:1,000) and HRP-conjugated goat anti-mouse secondary antibody (1:20,000) respectively. Image was developed using NaQ(TM) ECL Substrate Kit.
Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)

Western Blot: Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)[NBP3-51788] -

Western blotting analysis using Lymphotoxin beta R/TNFRSF3 antibody (1:1,000) and HRP-conjugated goat anti-mouse secondary antibody (1:20,000) respectively. Image was developed using NaQ(TM) ECL Substrate Kit.

Applications for Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Lymphotoxin beta R/TNFRSF3

LT-beta-R, also known as lymphotoxin beta receptor and tumor necrosis factor receptor superfamily member 3 is a 47 kD transmembrane protein containing 3 TNF receptor domains. The LT-beta-R is a receptor for the heterotrimeric lymphotoxin complex (composed of LT alpha and LT beta as well as LIGHT. LT-beta-R is highly expressed in the lung, liver, and kidney and moderately expressed expressed in the heart and testes. LT-beta-R is weakly expressed in the brain, thymus, spleen, and lymph nodes. The cytoplasmic tail of LT-beta-R interacts with TRAF3, TRAF4, and TRAF5 as well as the hepatitis C virus core protein. Ligand binding to LT-beta-R has been shown to induce apoptosis (via TRAF3 and TRAF5) and play a role in the development of lymphoid organs.

Long Name

Lymphotoxin beta Receptor

Alternate Names

LTBR, LymphotoxinbR, TNF RIII, TNF Rrp, TNFRSF3

Gene Symbol

LTBR

Additional Lymphotoxin beta R/TNFRSF3 Products

Product Documents for Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)

Certificate of Analysis

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Product Specific Notices for Lymphotoxin beta R/TNFRSF3 Antibody (24GB6730)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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