MagCellect Human CD3+ T Cell Isolation Kit
MagCellect Human CD3+ T Cell Isolation Kit Summary
The T cell receptor (TCR)/CD3 complex consists of two variable antigen-recognition receptor chains (TCR-alpha/TCR-beta or TCR-gamma/TCR-delta) that are non-covalently linked to at least four different invariant chains: CD3 gamma, CD3 delta, CD3 epsilon, and the CD3 zeta chain that exists as either a homodimer or as a heterodimer with its splice-variant the CD3 eta chain. The CD3 complex functions to transduce intracellular signals during TCR antigen recognition. CD3 is expressed early in thymocyte development, and on a subset of NK cells. CD3 epsilon is one of at least three invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction.
Citations for MagCellect Human CD3+ T Cell Isolation Kit
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Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro.
Authors: Danesh A, Inglis H, Jackman R, Wu S, Deng X, Muench M, Heitman J, Norris P
Blood, 2014;123(5):687-96. 2014
Mitogenic effect contributes to increased virulence of Streptococcus suis sequence type 7 to cause streptococcal toxic shock-like syndrome.
Authors: Zheng H, Ye C, Segura M, Gottschalk M, Xu J
Clin. Exp. Immunol., 2008;153(3):385-91. 2008
WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP).
Authors: de la Fuente MA, Sasahara Y, Calamito M, Anton IM, Elkhal A, Gallego MD, Suresh K, Siminovitch K, Ochs HD, Anderson KC, Rosen FS, Geha RS, Ramesh N
Proc. Natl. Acad. Sci. U.S.A., 2007;104(3):926-31. 2007
Transient regulatory T-cells: a state attained by all activated human T-cells.
Authors: Pillai V, Ortega SB, Wang CK, Karandikar NJ
Clin. Immunol., 2007;123(1):18-29. 2007
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