MCPH1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-89937

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all MCPH1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLPGGYSGSVKNRPTRHDVLDDSCDGFKDLIKPHEELKKSGRGKKPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGI

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23472065)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit MCPH1 Antibody - BSA Free (NBP1-89937) is a polyclonal antibody validated for use in IHC and WB. Anti-MCPH1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for MCPH1 Antibody - BSA Free

Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937]

Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937]

Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937]

Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937]

Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937] - Staining of human cerebellum shows moderate nuclear positivity in Purkinje and granular cell layers.
Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937]

Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937]

Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937] - Staining of human cerebral cortex shows moderate to strong nuclear positivity in neurons.
Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937]

Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937]

Immunohistochemistry-Paraffin: MCPH1 Antibody [NBP1-89937] - Staining of human liver shows no nuclear positivity in hepatocytes as expected.
MCPH1 Antibody - BSA Free Western Blot: MCPH1 Antibody - BSA Free [NBP1-89937]

Western Blot: MCPH1 Antibody - BSA Free [NBP1-89937]

Analysis in human cell line NTERA-2.

Applications for MCPH1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MCPH1

MCPH-1 was identified in a screen for negative regulators of hTERT (human telomerase) expression. It has been implicated in chromosome condensation and DNA damage induced cellular responses. It may play a role in neurogenesis and regulation of the size of the cerebral cortex. Defects in MCPH1 are the cause of primary microcephaly 1.

Long Name

Microcephalin 1

Alternate Names

BRIT1, MCT, Microcephalin

Gene Symbol

MCPH1

Additional MCPH1 Products

Product Documents for MCPH1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for MCPH1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for MCPH1 Antibody - BSA Free

Customer Reviews for MCPH1 Antibody - BSA Free

There are currently no reviews for this product. Be the first to review MCPH1 Antibody - BSA Free and earn rewards!

Have you used MCPH1 Antibody - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies