MEL-18 Antibody

Novus Biologicals | Catalog # NB100-1240

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all MEL-18 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KMTVNGAPVPPLT corresponding to C-Terminus according to NP_009075.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for MEL-18 Antibody

Western Blot: MEL-18 Antibody [NB100-1240]

Western Blot: MEL-18 Antibody [NB100-1240]

Western Blot: MEL-18 Antibody [NB100-1240] - A549 (A) and PD19 (B) cell lysate (RIPA buffer, 30ug total protein per lane). Detected by chemiluminescence.
Western Blot: MEL-18 Antibody [NB100-1240]

Western Blot: MEL-18 Antibody [NB100-1240]

Western Blot: MEL-18 Antibody [NB100-1240] - Analysis of MEL-18 in Human Lung lysate using this antibody at 1 ug/ ml.

Applications for MEL-18 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 2 ug/ml
Application Notes
WB: Approx. 40 kDa band observed in human lung lysates (calculated MW of 37.8 kDa band according to NP_009075.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MEL-18

MEL-18 is a transcriptional repressor that binds specifically to the DNA sequence 5'-GACTNGACT-3'. Mel18 has tumor suppressor activity and may play a role in cell proliferation and/or neural cell development. It regulates proliferation of early T progenitor cells by maintaining expression of HES1. Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells.

Alternate Names

MEL-18, polycomb group ring finger 2, polycomb group RING finger protein 2, RING finger protein 110DNA-binding protein Mel-18, RNF110MEL18, Zinc finger protein 144, ZNF144MGC10545

Entrez Gene IDs

7703 (Human)

Gene Symbol

PCGF2

UniProt

NP_009075. (Human)

Additional MEL-18 Products

Product Documents for MEL-18 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for MEL-18 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for MEL-18 Antibody

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FAQs

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