Key Product Details

Species Reactivity

Validated:

Human, Primate

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MEM-E/02

Format

BSA Free
View all MHC Class I Primary Antibodies »

Product Specifications

Immunogen

Recombinant human HLA-E denatured heavy chain.

Localization

Type I membrane protein.

Specificity

The antibody MEM-E/02 specifically reacts with denaturated heavy chain of human HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of all human cell types.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse MHC Class I Antibody (MEM-E/02) - BSA Free (NB500-304) is a monoclonal antibody validated for use in IHC and WB. Anti-MHC Class I Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.

Applications for MHC Class I Antibody (MEM-E/02) - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

5-10 ug/ml

Western Blot

1:1000
Application Notes
Predicted molecular weight: 43 kDa. Immunohistochemistry-Paraffin Heat antigen retrieval (sodium citrate); incubation with mAb: 1 hour / RT; detection DAB

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MHC Class I

HLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules.

Alternate Names

DKFZp686P19218, EA1.2, EA2.1, HLA class I histocompatibility antigen, alpha chain E, HLA class I histocompatibility antigen, E alpha chain, HLA-6.2, HLAE, lymphocyte antigen, major histocompatibility complex, class I, E, MHC, MHC class I antigen E, MHC HLA-E alpha-1, MHC HLA-E alpha-2.1, QA1

Entrez Gene IDs

3133 (Human)

Gene Symbol

HLA-E

Additional MHC Class I Products

Product Documents for MHC Class I Antibody (MEM-E/02) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for MHC Class I Antibody (MEM-E/02) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for MHC Class I Antibody (MEM-E/02) - BSA Free

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Protocols

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FAQs

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