MKK6/MEK6 Antibody [DyLight 350]

Name: MKK6/MEK6 Antibody [DyLight 350]
Brand: Novus Biologicals
SKU: AF16041D
Price: 549 USD
Availability: InStock

Novus Biologicals | Catalog # AF16041D

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Product Documents

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Knockout Validated, Western Blot

Label

DyLight 350 (Excitation = 353 nm, Emission = 432 nm)

Antibody Source

Polyclonal Goat IgG

View all MKK6 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human MKK6
Ser2-Asp334
Accession # P52564

Specificity

Detects human, mouse, and rat MKK6.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for MKK6/MEK6 Antibody [DyLight 350]

Application

Recommended Usage

Knockout Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MKK6

Mitogen-acitvated protein kinase kinase 6 (MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MAPKs require dual phosphorylation on threonine and tyrosine residues, an activation step carried out by MAPK kinase (1-2). MKK6, closely related to MKK3, efficiently phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines and environmental stress but not JNK or ERK (3). MTK1 phosphorylates MKK6 on serine 207 and threonine 211 (4).

Long Name

Mitogen-activated Protein Kinase Kinase 6

Alternate Names

MAP2K6, MEK6, PRKMK6, SAPKK3

Gene Symbol

MAP2K6

Additional MKK6 Products

Product Documents for MKK6/MEK6 Antibody [DyLight 350]

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Certificate of Analysis

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Product Specific Notices for MKK6/MEK6 Antibody [DyLight 350]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.