Mouse CCL2/JE/MCP-1 Quantikine ELISA Kit

Newer Version Available: MJE00B

Discontinued Product

MJE00 has been discontinued and is replaced by MJE00B.

Mouse/Rat CCL2/JE/MCP-1 Standard Curve
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Citations (159)
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Mouse CCL2/JE/MCP-1 Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (25 uL), Serum (25 uL)
Sensitivity
2 pg/mL
Assay Range
15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum)
Specificity
Natural and recombinant mouse and rat MCP-1
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Product Summary

The Quantikine Mouse/Rat CCL2/MCP-1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure MCP-1 in mouse or rat cell culture supernates and serum. It contains E. coli-expressed mouse MCP-1 and antibodies raised against the recombinant factor. This Immunoassay has been shown to accurately quantitate recombinant mouse MCP-1. Results obtained using natural mouse or rat MCP-1 showed dose response curves that were parallel to the standard curves obtained using the Quantikine mouse kit standards. These results indicate that this kit can be used to determine relative mass values for natural MCP-1.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 47.1 311 768 43.6 310 783
Standard Deviation 3.9 15.8 40.6 3.2 14.3 42.8
CV% 8.3 5.1 5.3 7.3 4.6 5.5

Recovery

The recovery of MCP-1 spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Mouse Cell Culture Supernates (n=6) 104 91-119
Mouse Serum (n=9) 99 89-113
Rat Cell Culture Supernates (n=4) 109 103-115
Rat Serum (n=4) 109 103-116

Linearity

To assess the linearity of the assay, samples containing and/or spiked with high concentrations of MCP-1 in each matrix were diluted with Calibrator Diluent and then assayed.
Mouse/Rat CCL2/JE/MCP-1 ELISA Linearity
Mouse CCL2/JE/MCP-1 ELISA Linearity

Data Examples

Mouse/Rat CCL2/JE/MCP-1 Standard Curve

Mouse CCL2/JE/MCP-1 ELISA Standard Curve

Product Datasheets

Preparation and Storage

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CCL2/JE/MCP-1

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

Entrez Gene IDs:
6347 (Human); 20296 (Mouse); 24770 (Rat); 403981 (Canine)
Alternate Names:
C-C motif chemokine ligand 2; CCL2; GDCF-2; HC11; HSMCR30; MCAF; Mcp1; MCP-1; SCYA2; SMC-CF
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 50 µL Assay Diluent
  4.   Add 50 µL of Assay Diluent to each well.

  5. 50 µL Standard, Control, or Sample
  6.   Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.

  8. 100 µL Conjugate
  9.   Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  10.   Aspirate and wash 5 times.

  11. 100 µL Substrate Solution
  12.   Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.

  13. 100 µL Stop Solution
  14.   Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Mouse CCL2/JE/MCP-1 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

159 Citations: Showing 1 - 10
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  1. NPY1R-targeted peptide-mediated delivery of a dual PPAR&alpha/&gamma agonist to adipocytes enhances adipogenesis and prevents diabetes progression
    Authors: S Wittrisch, N Klöting, K Mörl, R Chakaroun, M Blüher, AG Beck-Sicki
    Mol Metab, 2020;31(0):163-180.
    Species: Mouse
    Sample Types: Serum
  2. Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy
    Authors: L Shi, J Wang, N Ding, Y Zhang, Y Zhu, S Dong, X Wang, C Peng, C Zhou, L Zhou, X Li, H Shi, W Wu, X Long, C Wu, W Liao
    Nat Commun, 2019;10(1):5421.
    Species: Mouse
    Sample Types: Whole Blood
  3. Tripartite Motif 8 Deficiency Relieves Hepatic Ischaemia/reperfusion Injury via TAK1-dependent Signalling Pathways
    Authors: Q Tao, W Tianyu, Z Jiangqiao, C Zhongbao, M Xiaoxiong, Z Long, Z Jilin
    Int. J. Biol. Sci., 2019;15(8):1618-1629.
    Species: Mouse
    Sample Types: Serum
  4. Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis
    Authors: L Qin, Y Du, H Ding, A Haque, J Hicks, C Pedroza, C Mohan
    Arthritis Res. Ther., 2019;21(1):12.
    Species: Mouse
    Sample Types: Urine
  5. miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury
    Authors: Y Funahashi, N Kato, T Masuda, F Nishio, H Kitai, T Ishimoto, T Kosugi, N Tsuboi, N Matsuda, S Maruyama, K Kadomatsu
    Lab. Invest., 2019;0(0):.
    Species: Mouse
    Sample Types: Serum
  6. Impact of obesity on breast cancer recurrence and minimal residual disease
    Authors: BL Ecker, JY Lee, CJ Sterner, AC Solomon, DK Pant, F Shen, J Peraza, L Vaught, S Mahendra, GK Belka, TC Pan, KH Schmitz, LA Chodosh
    Breast Cancer Res., 2019;21(1):41.
    Species: Mouse
    Sample Types: Serum
  7. Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil
    Authors: K Taniguchi, Y Ando, H Nobori, S Toba, T Noshi, M Kobayashi, M Kawai, R Yoshida, A Sato, T Shishido, A Naito, K Matsuno, M Okamatsu, Y Sakoda, H Kida
    Sci Rep, 2019;9(1):3466.
    Species: Mouse
    Sample Types: Tissue Homogenates
  8. Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases
    Authors: HH Guo, CL Feng, WX Zhang, ZG Luo, HJ Zhang, TT Zhang, C Ma, Y Zhan, R Li, S Wu, Z Abliz, C Li, XL Li, XL Ma, LL Wang, WS Zheng, YX Han, JD Jiang
    Nat Commun, 2019;10(1):1981.
    Species: Mouse
    Sample Types: Plasma
  9. Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells
    Authors: N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald
    JCI Insight, 2019;0(0):.
    Species: Mouse
    Sample Types: Serum
  10. Gestational oxidative stress protects against adult obesity and insulin resistance
    Authors: LG Dimova, S Battista, T Plösch, RA Kampen, F Liu, RN Verkaik-Sc, D Pratico, HJ Verkade, UJF Tietge
    Redox Biol, 2019;28(0):101329.
    Species: Mouse
    Sample Types: Plasma
  11. Mesothelial Cell HIF1alpha Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk
    Authors: PC Hart, HA Kenny, N Grassl, KM Watters, LM Litchfield, F Coscia, I Blaženovi?, L Ploetzky, O Fiehn, M Mann, E Lengyel, IL Romero
    Cell Rep, 2019;29(12):4086-4098.e6.
    Species: Mouse
    Sample Types: Tissue Lysates
  12. Cromolyn sodium delays disease onset and is neuroprotective in the SOD1G93A Mouse Model of amyotrophic lateral sclerosis
    Authors: EJ Granucci, A Griciuc, KA Mueller, AN Mills, H Le, AM Dios, D McGinty, J Pereira, D Elmaleh, JD Berry, S Paganoni, ME Cudkowicz, RE Tanzi, G Sadri-Vaki
    Sci Rep, 2019;9(1):17728.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  13. Change of surfactant protein D and A after renal ischemia reperfusion injury
    Authors: IM Imtiazul, R Asma, JH Lee, NJ Cho, S Park, HY Song, HW Gil
    PLoS ONE, 2019;14(12):e0227097.
    Species: Mouse
    Sample Types: Serum
  14. Infection perturbs Bach2- and Bach1-dependent erythroid lineage 'choice' to cause anemia
    Authors: H Kato, A Itoh-Nakad, M Matsumoto, Y Ishii, M Watanabe-M, M Ikeda, R Ebina-Shib, Y Sato, M Kobayashi, H Nishizawa, K Suzuki, A Muto, T Fujiwara, Y Nannya, L Malcovati, M Cazzola, S Ogawa, H Harigae, K Igarashi
    Nat. Immunol., 2018;19(10):1059-1070.
    Species: Mouse
    Sample Types: Serum
  15. Inflammatory Monocytes Drive Influenza A Virus-Mediated Lung Injury in Juvenile Mice
    Authors: BM Coates, KL Staricha, CM Koch, Y Cheng, DK Shumaker, GRS Budinger, H Perlman, AV Misharin, KM Ridge
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  16. MicroRNA-33 regulates the population of peripheral inflammatory Ly6Chigh monocytes through dual pathways
    Authors: O Baba, T Horie, T Nakao, D Hakuno, Y Nakashima, H Nishi, Y Kuwabara, M Nishiga, T Nishino, Y Ide, F Nakazeki, S Koyama, M Kimura, R Hanada, M Kawahara, T Kimura, K Ono
    Mol. Cell. Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  17. Macrophages orchestrate breast cancer early dissemination and metastasis
    Authors: N Linde, M Casanova-A, MS Sosa, A Mortha, A Rahman, E Farias, K Harper, E Tardio, I Reyes Torr, J Jones, J Condeelis, M Merad, JA Aguirre-Gh
    Nat Commun, 2018;9(1):21.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  18. Ginkgo biloba extracts prevent aortic rupture in angiotensin II-infused hypercholesterolemic mice
    Authors: XF Huang, SZ Zhang, YY You, N Zhang, H Lu, A Daugherty, XJ Xie
    Acta Pharmacol. Sin., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  19. Effect of Thrombin-Induced MCP-1 and MMP-3 Production Via PAR1 Expression in Murine Intervertebral Discs
    Authors: Y Takayama, T Ando, J Ichikawa, H Haro
    Sci Rep, 2018;8(1):11320.
    Species: Mouse
    Sample Types: Tissue Supernates
  20. Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet
    Authors: CR Bae, J Hino, H Hosoda, C Son, H Makino, T Tokudome, T Tomita, K Hosoda, M Miyazato, K Kangawa
    Sci Rep, 2018;8(1):2093.
    Species: Mouse
    Sample Types: Serum
  21. The anti-asthmatic drug, montelukast, modifies the neurogenic potential in the young healthy and irradiated brain
    Authors: Y Eriksson, M Boström, Å Sandelius, K Blennow, H Zetterberg, G Kuhn, M Kalm
    Cell Death Dis, 2018;9(7):775.
    Species: Mouse
    Sample Types: Tissue Homogenates
  22. XRCC3 polymorphism is associated with hypertension-induced left ventricular hypertrophy
    Authors: A Ariyandy, C Sakai, M Ishida, R Mizuta, K Miyagawa, S Tashiro, A Kinomura, K Hiraaki, K Ueda, M Yoshizumi, T Ishida
    Hypertens. Res., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  23. Pentosan Polysulfate Treatment of Mucopolysaccharidosis Type IIIA Mice
    Authors: N Guo, V DeAngelis, C Zhu, EH Schuchman, CM Simonaro
    JIMD Rep, 2018;0(0):.
    Species: Mouse
    Sample Types: Plasma
  24. Monocyte infiltration rather than microglia proliferation dominates the early immune response to rapid photoreceptor degeneration
    Authors: SJ Karlen, EB Miller, X Wang, ES Levine, RJ Zawadzki, ME Burns
    J Neuroinflammation, 2018;15(1):344.
    Species: Mouse
    Sample Types: Tissue Homogenates
  25. Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury
    Authors: J Lou, Y Hu, MD Wu, LQ Che, YF Wu, Y Zhao, BP Tian, ZQ Bao, C Zhu, YP Wu, LL He, CX Bai, J Zhou, SM Ying, W Li, ZH Chen, DX Chen, A Dorling, HH Shen
    Acta Pharmacol. Sin., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  26. PAR2 (Protease-Activated Receptor 2) Deficiency Attenuates Atherosclerosis in Mice
    Authors: SM Jones, A Mann, K Conrad, K Saum, DE Hall, LM McKinney, N Robbins, J Thompson, AD Peairs, E Camerer, KJ Rayner, M Tranter, N Mackman, AP Owens
    Arterioscler. Thromb. Vasc. Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: Plasma
  27. TIM?4 blockade of KCs combined with exogenous TGF?β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts
    Authors: H Wu, X Xu, J Li, J Gong, M Li
    Int. J. Mol. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  28. SDF-1 is an Autocrine Insulin-Desensitizing Factor in Adipocytes
    Authors: J Shin, A Fukuhara, T Onodera, S Kita, C Yokoyama, M Otsuki, I Shimomura
    Diabetes, 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Capture
  29. Immunization with Pseudomonas aeruginosa outer membrane vesicles stimulates protective immunity in mice
    Authors: X Zhang, F Yang, J Zou, W Wu, H Jing, Q Gou, H Li, J Gu, Q Zou, J Zhang
    Vaccine, 2018;36(8):1047-1054.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Capture
  30. SARM1 deletion restrains NAFLD induced by high fat diet (HFD) through reducing inflammation, oxidative stress and lipid accumulation
    Authors: ZG Pan, XS An
    Biochem. Biophys. Res. Commun., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
    Applications: ELISA Capture
  31. Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates
    Authors: PX Wang, YX Ji, XJ Zhang, LP Zhao, ZZ Yan, P Zhang, LJ Shen, X Yang, J Fang, S Tian, XY Zhu, J Gong, X Zhang, QF Wei, Y Wang, J Li, L Wan, Q Xie, ZG She, Z Wang, Z Huang, H Li
    Nat. Med, 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  32. The Effect of Low-Dose Proteasome Inhibition on Pre-Existing Atherosclerosis in LDL Receptor-Deficient Mice
    Authors: N Wilck, M Fechner, C Dan, V Stangl, K Stangl, A Ludwig
    Int J Mol Sci, 2017;18(4):.
    Species: Mouse
    Sample Types: Serum
  33. Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis
    Authors: R Cinar, BR Gochuico, MR Iyer, T Jourdan, T Yokoyama, JK Park, NJ Coffey, H Pri-Chen, G Szanda, Z Liu, K Mackie, WA Gahl, G Kunos
    JCI Insight, 2017;2(8):.
    Species: Mouse
    Sample Types: BALF
  34. Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology
    Authors: SJ Whitfield, C Taylor, JE Risdall, GD Griffiths, JT Jones, ED Williamson, S Rijpkema, L Saraiva, S Vessillier, AC Green, AJ Carter
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  35. The Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo
    Authors: N Lavender, J Yang, SC Chen, J Sai, CA Johnson, P Owens, GD Ayers, A Richmond
    BMC Cancer, 2017;17(1):88.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  36. The scavenging chemokine receptor ACKR2 has a significant impact on acute mortality rate and early lesion development after traumatic brain injury
    Authors: TM Woodcock, T Frugier, TT Nguyen, BD Semple, N Bye, M Massara, B Savino, R Besio, C Sobacchi, M Locati, MC Morganti-K
    PLoS ONE, 2017;12(11):e0188305.
    Species: Mouse
    Sample Types: Tissue Homogenates
  37. Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice
    Authors: X He, S Dworski, C Zhu, V DeAngelis, A Solyom, JA Medin, CM Simonaro, EH Schuchman
    BBA Clin, 2017;7(0):85-96.
    Species: Mouse
    Sample Types: Plasma
  38. Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa
    Authors: S Hopp, MW Nolte, C Stetter, C Kleinschni, AL Sirén, C Albert-Wei
    J Neuroinflammation, 2017;14(1):39.
    Species: Mouse
    Sample Types: Plasma
  39. Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes
    Authors: T Hara, HJ Nakaoka, T Hayashi, K Mimura, D Hoshino, M Inoue, F Nagamura, Y Murakami, M Seiki, T Sakamoto
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  40. Kruppel-like factor 6 promotes macrophage-mediated inflammation by suppressing B cell leukemia/lymphoma 6 expression
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  41. Monocyte chemotactic protein-1 deficiency reduces spontaneous metastasis of Lewis lung carcinoma in mice fed a high-fat diet
    Oncotarget, 2016;7(17):24792-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  42. Toll-like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice
    Authors: S Nakamura, N Iwanaga, M Seki, K Fukudome, K Oshima, T Miyazaki, K Izumikawa, K Yanagihara, Y Miyazaki, H Mukae, S Kohno
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  43. Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-? Stimulated Gene/Protein 6
    Sci Rep, 2016;6(0):38438.
    Species: Mouse
    Sample Types: Serum
  44. Soluble Fn14 Is Detected and Elevated in Mouse and Human Kidney Disease
    PLoS ONE, 2016;11(5):e0155368.
    Species: Mouse
    Sample Types: Urine
  45. Targeting Tumor Cells with Anti-CD44 Antibody Triggers Macrophage-Mediated Immune Modulatory Effects in a Cancer Xenograft Model
    PLoS ONE, 2016;11(7):e0159716.
    Species: Mouse
    Sample Types: Tissue Homogenates
  46. MicroRNA-33 suppresses CCL2 expression in chondrocytes
    Authors: M Wei, Q Xie, J Zhu, T Wang, F Zhang, Y Cheng, D Guo, Y Wang, L Mo, S Wang
    Biosci Rep, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  47. Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury
    PLoS ONE, 2016;11(12):e0166770.
    Species: Mouse
    Sample Types: Tissue Homogenates
  48. Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis.
    Authors: Liao K, Guo M, Niu F, Yang L, Callen S, Buch S
    J Neuroinflammation, 2015;13(1):33.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  49. IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells.
    Authors: Besnard A, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw T, Couper K, Ryffel B, Liew F
    PLoS Pathog, 2015;11(2):e1004607.
    Species: Mouse
    Sample Types: Serum
  50. Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
    Authors: Charolidi N, Schilling T, Eder C
    PLoS ONE, 2015;10(5):e0128463.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. Mesenchymal stem/stromal cells protect against autoimmunity via CCL2-dependent recruitment of myeloid-derived suppressor cells.
    Authors: Lee H, Ko J, Jeong H, Ko A, Kim M, Wee W, Yoon S, Oh J
    J Immunol, 2015;194(8):3634-45.
    Species: Mouse
    Sample Types: Tissue Homogenates
  52. Renal Lipotoxicity-Associated Inflammation and Insulin Resistance Affects Actin Cytoskeleton Organization in Podocytes.
    Authors: Martinez-Garcia C, Izquierdo-Lahuerta A, Vivas Y, Velasco I, Yeo T, Chen S, Medina-Gomez G
    PLoS ONE, 2015;10(11):e0142291.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  53. Cannabinoid receptor 1 is a major mediator of renal fibrosis.
    Authors: Lecru L, Desterke C, Grassin-Delyle S, Chatziantoniou C, Vandermeersch S, Devocelle A, Vernochet A, Ivanovski N, Ledent C, Ferlicot S, Dalia M, Said M, Beaudreuil S, Charpentier B, Vazquez A, Giron-Michel J, Azzarone B, Durrbach A, Francois H
    Kidney Int, 2015;88(1):72-84.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  54. Differential Contribution of Acute and Chronic Inflammation to the Development of Murine Mammary 4T1 Tumors.
    Authors: Rodrigues Viana C, Castro P, Marques S, Paz Lopes M, Goncalves R, Campos P, Andrade S
    PLoS ONE, 2015;10(7):e0130809.
    Species: Mouse
    Sample Types: Tissue Homogenates
  55. Adenovirus 36 attenuates weight loss from exercise but improves glycemic control by increasing mitochondrial activity in the liver.
    Authors: Na, Ha-Na, Hong, Young-Mi, Ye, Michael, Park, Sooho, Kim, In-Beom, Nam, Jae-Hwan
    PLoS ONE, 2015;9(12):e114534.
    Species: Mouse
    Sample Types: Tissue Homogenates
  56. CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
    Authors: Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A
    J Immunol, 2014;192(8):3816-27.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  57. Effects of a high-fat diet on spontaneous metastasis of Lewis lung carcinoma in plasminogen activator inhibitor-1 deficient and wild-type mice.
    Authors: Yan L, DeMars L
    PLoS ONE, 2014;9(10):e110869.
    Species: Mouse
    Sample Types: Plasma
  58. Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma.
    Authors: Rydell-Tormanen K, Andreasson K, Hesselstrand R, Westergren-Thorsson G
    Sci Rep, 2014;4(0):6383.
    Species: Mouse
    Sample Types: Serum
  59. Rho-kinase activation in leukocytes plays a pivotal role in myocardial ischemia/reperfusion injury.
    Authors: Kitano K, Usui S, Ootsuji H, Takashima S, Kobayashi D, Murai H, Furusho H, Nomura A, Kaneko S, Takamura M
    PLoS ONE, 2014;9(3):e92242.
    Species: Mouse
    Sample Types: Serum
  60. Activation of A1-adenosine receptors promotes leukocyte recruitment to the lung and attenuates acute lung injury in mice infected with influenza A/WSN/33 (H1N1) virus.
    Authors: Aeffner F, Woods P, Davis I
    J Virol, 2014;88(17):10214-27.
    Species: Mouse
    Sample Types: BALF
  61. Combined effect of hyperfiltration and renin angiotensin system activation on development of chronic kidney disease in diabetic db/db mice.
    Authors: Hartono S, Knudsen B, Lerman L, Textor S, Grande J
    BMC Nephrol, 2014;15(0):58.
    Species: Mouse
    Sample Types: Protein
  62. Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL.
    Authors: Ohba T, Cole H, Cates J, Slosky D, Haro H, Ando T, Schwartz H, Schoenecker J
    J Bone Miner Res, 2014;29(6):1431-45.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  63. Chemokine expression in peripheral tissues from the monosodium iodoacetate model of chronic joint pain.
    Authors: Dawes, John M, Kiesewetter, Hannes, Perkins, James R, Bennett, David L, McMahon, Stephen
    Mol Pain, 2013;9(0):57.
    Species: Rat
    Sample Types: Tissue Homogenates
  64. Spironolactone attenuates bleomycin-induced pulmonary injury partially via modulating mononuclear phagocyte phenotype switching in circulating and alveolar compartments.
    Authors: Ji W, Ma Y, Zhou X, Zhang Y, Lu R, Guo Z, Sun H, Hu D, Yang G, Li Y, Wei L
    PLoS ONE, 2013;8(11):e81090.
    Species: Mouse
    Sample Types: BALF
  65. Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
    Authors: Lin J, Sun B, Jiang C, Hong H, Zheng Y
    Biochem Biophys Res Commun, 2013;441(4):897-903.
    Species: Mouse
    Sample Types: Serum
  66. Macrophage cathepsin K promotes prostate tumor progression in bone.
    Authors: Herroon, M K, Rajagurubandara, E, Rudy, D L, Chalasani, A, Hardaway, A L, Podgorski, I
    Oncogene, 2013;32(12):1580-93.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  67. Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration.
    Authors: Maina, Virginia, Marrella, Veronica, Mantero, Stefano, Cassani, Barbara, Fontana, Elena, Anselmo, Achille, Del Prete, Annalisa, Sozzani, Silvano, Vezzoni, Paolo, Poliani, Pietro L, Villa, Anna
    J Leukoc Biol, 2013;94(6):1221-30.
    Species: Mouse
    Sample Types: Tissue Homogenates
  68. Decorin potentiates interferon-gamma activity in a model of allergic inflammation.
    Authors: Bocian C, Urbanowitz A, Owens R, Iozzo R, Gotte M, Seidler D
    J Biol Chem, 2013;288(18):12699-711.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  69. Stimulation of GABA-induced Ca2+ influx enhances maturation of human induced pluripotent stem cell-derived neurons.
    Authors: Rushton D, Mattis V, Svendsen C, Allen N, Kemp P
    PLoS ONE, 2013;8(11):e81031.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  70. Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells.
    Authors: Yoshimura T, Howard O, Ito T, Kuwabara M, Matsukawa A, Chen K, Liu Y, Liu M, Oppenheim J, Wang J
    PLoS ONE, 2013;8(3):e58791.
    Species: Mouse
    Sample Types: Serum
  71. Antisense oligonucleotide treatment enhances the recovery of acute lung injury through IL-10-secreting M2-like macrophage-induced expansion of CD4+ regulatory T cells.
    Authors: Guo Z, Wen Z, Qin A, Zhou Y, Liao Z, Liu Z, Liang Y, Ren T, Xu L
    J Immunol, 2013;190(8):4337-48.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  72. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
    Authors: Gottfries J, Melgar S, Michaelsson E
    PLoS ONE, 2012;7(1):e30005.
    Species: Mouse
    Sample Types: Tissue Homogenates
  73. Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease.
    Authors: Chantrathammachart P, Mackman N, Sparkenbaugh E
    Blood, 2012;120(3):636-46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  74. The synthetic triterpenoid CDDO-methyl ester delays estrogen receptor-negative mammary carcinogenesis in polyoma middle T mice.
    Authors: Tran K, Risingsong R, Royce D
    Cancer Prev Res (Phila), 2012;5(5):726-34.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  75. Inhalative vs. systemic IL-10 administration: differences in the systemic inflammatory response and end-organ inflammation following hemorrhagic shock.
    Authors: Pfeifer R, Lichte P, Schreiber H, Sellei R, Schmidt J, Dombroski D, Pape H, Kobbe P
    Cytokine, 2012;60(1):266-70.
    Species: Mouse
    Sample Types: Serum
  76. Chitin elicits CCL2 from airway epithelial cells and induces CCR2-dependent innate allergic inflammation in the lung.
    J. Immunol., 2012;189(5):2545-52.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  77. Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor.
    J. Exp. Med., 2012;209(8):1493-503.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  78. Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice.
    Mol. Cell. Endocrinol., 2012;358(1):127-34.
    Species: Mouse
    Sample Types: Serum
  79. Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent.
    Authors: Provoost S, Maes T, Joos GF, Tournoy KG
    J. Allergy Clin. Immunol., 2012;129(2):483-91.
    Species: Mouse
    Sample Types: BALF
  80. Abscisic acid regulates inflammation via ligand-binding domain-independent activation of peroxisome proliferator-activated receptor gamma.
    Authors: Bassaganya-Riera J, Guri AJ, Lu P, Climent M, Carbo A, Sobral BW, Horne WT, Lewis SN, Bevan DR, Hontecillas R
    J. Biol. Chem., 2011;286(4):2504-16.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  81. The Role of ChemR23 in the Induction and Resolution of Cigarette Smoke-Induced Inflammation.
    Authors: Demoor T, Bracke KR, Dupont LL
    J. Immunol., 2011;186(9):5457-67.
    Species: Mouse
    Sample Types: BALF
  82. Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization.
    Authors: Liu J, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS
    J. Biol. Chem., 2011;286(23):20991-1001.
    Species: Mouse
    Sample Types: Tissue Homogenates
  83. Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice.
    Authors: Deng Y, Edin ML, Theken KN, Schuck RN, Flake GP, Kannon MA, DeGraff LM, Lih FB, Foley J, Bradbury JA, Graves JP, Tomer KB, Falck JR, Zeldin DC, Lee CR
    FASEB J., 2011;25(2):703-13.
    Species: Mouse
    Sample Types: Cell Lysates
  84. Differential host determinants contribute to the pathogenesis of 2009 pandemic H1N1 and human H5N1 influenza A viruses in experimental mouse models.
    Authors: Otte A, Sauter M, Alleva L, Baumgarte S, Klingel K, Gabriel G
    Am. J. Pathol., 2011;179(1):230-9.
    Species: Mouse
    Sample Types: Serum
  85. Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
    Authors: Zhu M, Hug C, Kasahara DI
    Am. J. Respir. Cell Mol. Biol., 2010;43(4):487-97.
    Species: Mouse
    Sample Types: BALF
  86. Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
    Authors: Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch J, Schirmacher P, Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Hasler R, Becker C, Neurath MF, Reiss K, Saftig P, Scheller J, Rose-John S
    J. Exp. Med., 2010;207(8):1617-24.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  87. Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
    Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
    J. Invest. Dermatol., 2010;130(3):866-75.
    Species: Mouse
    Sample Types: Tissue Homogenates
  88. Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases.
    Authors: Massberg S, Grahl L, von Bruehl ML, Manukyan D, Pfeiler S, Goosmann C, Brinkmann V, Lorenz M, Bidzhekov K, Khandagale AB, Konrad I, Kennerknecht E, Reges K, Holdenrieder S, Braun S, Reinhardt C, Spannagl M, Preissner KT, Engelmann B
    Nat. Med., 2010;16(8):887-96.
    Species: Mouse
    Sample Types: Plasma
  89. An increase in the circulating concentration of monocyte chemoattractant protein-1 elicits systemic insulin resistance irrespective of adipose tissue inflammation in mice.
    Authors: Tateya S, Tamori Y, Kawaguchi T, Kanda H, Kasuga M
    Endocrinology, 2010;151(3):971-9.
    Species: Mouse
    Sample Types: Plasma
  90. Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia.
    Authors: Schabbauer G, Matt U, Gunzl P, Warszawska J, Furtner T, Hainzl E, Elbau I, Mesteri I, Doninger B, Binder BR, Knapp S
    J. Immunol., 2010;185(1):468-76.
    Species: Mouse
    Sample Types: BALF
  91. Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
    Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
    Cytokine, 2010;49(3):256-63.
    Species: Mouse
    Sample Types: BALF
  92. Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
    Authors: Pini M, Fantuzzi G
    J. Leukoc. Biol., 2010;87(1):51-8.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  93. Combined inhibition of janus kinase 1/2 for the treatment of JAK2V617F-driven neoplasms: selective effects on mutant cells and improvements in measures of disease severity.
    Authors: Liu PC, Caulder E, Li J, Waeltz P, Margulis A, Wynn R, Becker-Pasha M, Li Y, Crowgey E, Hollis G, Haley P, Sparks RB, Combs AP, Rodgers JD, Burn TC, Vaddi K, Fridman JS
    Clin. Cancer Res., 2009;15(22):6891-900.
    Species: Mouse
    Sample Types: Plasma
  94. JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain.
    Authors: Gao YJ, Zhang L, Samad OA, Suter MR, Yasuhiko K, Xu ZZ, Park JY, Lind AL, Ma Q, Ji RR
    J. Neurosci., 2009;29(13):4096-108.
    Species: Mouse
    Sample Types: Cell Lysates
  95. Urinary excretion of liver type fatty acid binding protein accurately reflects the degree of tubulointerstitial damage.
    Authors: Yokoyama T, Kamijo-Ikemori A, Sugaya T, Hoshino S, Yasuda T, Kimura K
    Am. J. Pathol., 2009;174(6):2096-106.
    Species: Mouse
    Sample Types: Tissue Homogenates
  96. Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
    Authors: Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T
    Am. J. Physiol. Heart Circ. Physiol., 2009;296(5):H1329-35.
    Species: Mouse
    Sample Types: Serum
  97. Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice.
    Authors: Gram K, Yang S, Steiner M, Somani A, Hawgood S, Blazar BR, Panoskaltsis-Mortari A, Haddad IY
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(2):L167-75.
    Species: Mouse
    Sample Types: BALF
  98. Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma.
    Authors: Ryman-Rasmussen JP, Tewksbury EW, Moss OR, Cesta MF, Wong BA, Bonner JC
    Am. J. Respir. Cell Mol. Biol., 2009;40(3):349-58.
    Species: Mouse
    Sample Types: BALF
  99. Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse.
    Authors: Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH
    Atherosclerosis, 2009;204(1):147-55.
    Species: Mouse
    Sample Types: Plasma
  100. TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
    Authors: Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, Henson PM, Janssen WJ
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(4):L586-95.
    Species: Mouse
    Sample Types: BALF
  101. Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
    Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
    J. Neuroimmunol., 2009;208(1):54-60.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  102. Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy.
    Authors: Yang SJ, IglayReger HB, Kadouh HC, Bodary PF
    Diabetologia, 2009;52(0):972-81.
    Species: Mouse
    Sample Types: Serum
  103. Prevention of ocular inflammation in endotoxin-induced uveitis with resveratrol by inhibiting oxidative damage and nuclear factor-kappaB activation.
    Authors: Kubota S, Kurihara T, Mochimaru H, Satofuka S, Noda K, Ozawa Y, Oike Y, Ishida S, Tsubota K
    Invest. Ophthalmol. Vis. Sci., 2009;50(7):3512-9.
    Species: Mouse
    Sample Types: Cell Lysates
  104. Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.
    Authors: Shweke N, Boulos N, Jouanneau C, Vandermeersch S, Melino G, Dussaule JC, Chatziantoniou C, Ronco P, Boffa JJ
    Am. J. Pathol., 2008;173(3):631-42.
    Species: Mouse
    Sample Types: Tissue Homogenates
  105. (Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.
    Authors: Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S
    Am. J. Pathol., 2008;173(6):1911-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  106. The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.
    Authors: Bose M, Lambert JD, Ju J, Reuhl KR, Shapses SA, Yang CS
    J. Nutr., 2008;138(9):1677-83.
    Species: Mouse
    Sample Types: Plasma
  107. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
    Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
    Eur. J. Pharmacol., 2008;590(1):400-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  108. A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
    Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
    Arthritis Rheum., 2008;58(11):3510-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  109. Adverse functions of IL-17A in experimental sepsis.
    Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
    FASEB J., 2008;22(7):2198-205.
    Species: Mouse
    Sample Types: Plasma
  110. Chemical sympathectomy increases susceptibility to ocular herpes simplex virus type 1 infection.
    Authors: Templeton A, Nguyen G, Ash JD, Straub RH, Carr DJ
    J. Neuroimmunol., 2008;197(1):37-46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  111. CD36/fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury.
    Authors: Kim E, Tolhurst AT, Qin LY, Chen XY, Febbraio M, Cho S
    J. Neurosci., 2008;28(18):4661-70.
    Species: Mouse
    Sample Types: Plasma
  112. Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
    Authors: Zhang H, Moochhala SM, Bhatia M
    J. Immunol., 2008;181(6):4320-31.
    Species: Mouse
    Sample Types: Tissue Homogenates
  113. Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection.
    Authors: Di Liberto D, Locati M, Caccamo N, Vecchi A, Meraviglia S, Salerno A, Sireci G, Nebuloni M, Caceres N, Cardona PJ, Dieli F, Mantovani A
    J. Exp. Med., 2008;205(9):2075-84.
    Species: Mouse
    Sample Types: Serum
  114. Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
    Authors: Leoni G, Patel HB, Sampaio AL, Gavins FN, Murray JF, Grieco P, Getting SJ, Perretti M
    FASEB J., 2008;22(12):4228-38.
    Species: Mouse
    Sample Types: Plasma
  115. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
    Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
    Am. J. Pathol., 2008;172(5):1209-21.
    Species: Mouse
    Sample Types: Tissue Homogenates
  116. Deficiency of immunophilin FKBP52 promotes endometriosis.
    Authors: Hirota Y, Tranguch S, Daikoku T, Hasegawa A, Osuga Y, Taketani Y, Dey SK
    Am. J. Pathol., 2008;173(6):1747-57.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  117. IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
    Authors: Zheng T, Liu W, Oh SY, Zhu Z, Hu B, Homer RJ, Cohn L, Grusby MJ, Elias JA
    J. Immunol., 2008;180(1):522-9.
    Species: Mouse
    Sample Types: BALF
  118. Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin.
    Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Ohno S, Oike Y, Ishida S
    Invest. Ophthalmol. Vis. Sci., 2008;49(4):1679-85.
    Species: Mouse
    Sample Types: Tissue Homogenates
  119. Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
    Authors: Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Flaherty KR, Martinez FJ, Hogaboam CM
    Am. J. Pathol., 2007;170(4):1152-64.
    Species: Mouse
    Sample Types: Tissue Homogenates
  120. Monocyte chemoattractant protein-1-induced tissue inflammation is critical for the development of renal injury but not type 2 diabetes in obese db/db mice.
    Authors: Chow FY, Ma FY, Ozols E, Tesch GH
    Diabetologia, 2007;50(2):471-80.
    Species: Mouse
    Sample Types: Urine
  121. Keratinocyte growth factor protects against elastase-induced pulmonary emphysema in mice.
    Authors: Plantier L, Marchand-Adam S, Antico VG, Boyer L, De Coster C, Marchal J, Bachoual R, Mailleux A, Boczkowski J, Crestani B
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(5):L1230-9.
    Species: Mouse
    Sample Types: BALF
  122. Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation.
    Authors: Robays LJ, Maes T, Lebecque S, Lira SA, Kuziel WA, Brusselle GG, Joos GF, Vermaelen KV
    J. Immunol., 2007;178(8):5305-11.
    Species: Mouse
    Sample Types: BALF
  123. Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
    Authors: Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR
    Transplantation, 2007;84(10):1279-87.
    Species: Mouse
    Sample Types: Serum
  124. Important role of apoptosis signal-regulating kinase 1 in ischemic acute kidney injury.
    Authors: Terada Y, Inoshita S, Kuwana H, Kobayashi T, Okado T, Ichijo H, Sasaki S
    Biochem. Biophys. Res. Commun., 2007;364(4):1043-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  125. Macular pigment lutein is antiinflammatory in preventing choroidal neovascularization.
    Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Umezawa K, Ohno S, Oike Y, Ishida S
    Arterioscler. Thromb. Vasc. Biol., 2007;27(12):2555-62.
    Species: Mouse
    Sample Types: Tissue Homogenates
  126. Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses.
    Authors: Menetski J, Mistry S, Lu M, Mudgett JS, Ransohoff RM, Demartino JA, Macintyre DE, Abbadie C
    Neuroscience, 2007;149(3):706-14.
    Species: Mouse
    Sample Types: Serum
  127. Upregulation of VEGF in murine retina via monocyte recruitment after retinal scatter laser photocoagulation.
    Authors: Itaya M, Sakurai E, Nozaki M, Yamada K, Yamasaki S, Asai K, Ogura Y
    Invest. Ophthalmol. Vis. Sci., 2007;48(12):5677-83.
    Species: Mouse
    Sample Types: Tissue Homogenates
  128. Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
    Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z
    J. Allergy Clin. Immunol., 2007;119(1):123-31.
    Species: Mouse
    Sample Types: BALF
  129. TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
    Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
    J. Immunol., 2007;178(10):6252-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  130. Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration.
    Authors: Qin L, Wu X, Block ML, Liu Y, Breese GR, Hong JS, Knapp DJ, Crews FT
    Glia, 2007;55(5):453-62.
    Species: Mouse
    Sample Types: Tissue Homogenates
  131. Pharmacological inhibition of epsilon PKC suppresses chronic inflammation in murine cardiac transplantation model.
    Authors: Koyanagi T, Noguchi K, Ootani A, Inagaki K, Robbins RC, Mochly-Rosen D
    J. Mol. Cell. Cardiol., 2007;43(4):517-22.
    Species: Mouse
    Sample Types: Tissue Homogenates
  132. Atheroprotective role of interleukin-6 in diet- and/or pathogen-associated atherosclerosis using an ApoE heterozygote murine model.
    Authors: Madan M, Bishayi B, Hoge M, Amar S
    Atherosclerosis, 2007;197(2):504-14.
    Species: Mouse
    Sample Types: Serum
  133. Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
    Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
    Am. J. Pathol., 2007;170(3):1003-17.
    Species: Mouse
    Sample Types: Serum
  134. Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.
    Authors: Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A
    Proc. Natl. Acad. Sci. U.S.A., 2007;104(7):2319-24.
    Species: Mouse
    Sample Types: Tissue Homogenates
  135. The chemokine decoy receptor M3 blocks CC chemokine ligand 2 and CXC chemokine ligand 13 function in vivo.
    Authors: Martin AP, Canasto-Chibuque C, Shang L, Rollins BJ, Lira SA
    J. Immunol., 2006;177(10):7296-302.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  136. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
    Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
    J. Exp. Med., 2006;203(12):2763-77.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  137. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
    Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1246-55.
    Species: Mouse
    Sample Types: Tissue Homogenates
  138. Altered postnatal lung development in C3H/HeJ mice.
    Authors: Sampath V, Davis K, Senft AP, Richardson TR, Kitzmiller JA, Berclaz PY, Korfhagen TR
    Pediatr. Res., 2006;60(6):663-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  139. Type I IFN modulates host defense and late hyperinflammation in septic peritonitis.
    Authors: Weighardt H, Kaiser-Moore S, Schlautkotter S, Rossmann-Bloeck T, Schleicher U, Bogdan C, Holzmann B
    J. Immunol., 2006;177(8):5623-30.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  140. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
    Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
    Biochem. Biophys. Res. Commun., 2006;345(3):1122-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  141. Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis.
    Authors: Drmotova M, Rehnstrom E, Jansson L
    Cytokine, 2006;35(5):275-83.
    Species: Mouse
    Sample Types: Tissue Homogenates
  142. Contribution of T cell subsets to the pathophysiology of Pneumocystis-related immunorestitution disease.
    Authors: Bhagwat SP, Gigliotti F, Xu H, Wright TW
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1256-66.
    Species: Mouse
    Sample Types: BALF
  143. Obligatory role for interleukin-13 in obstructive lesion development in airway allografts.
    Authors: Lama VN, Harada H, Badri LN, Flint A, Hogaboam CM, McKenzie A, Martinez FJ, Toews GB, Moore BB, Pinsky DJ
    Am. J. Pathol., 2006;169(1):47-60.
    Species: Mouse
    Sample Types: Tissue Homogenates
  144. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
    Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
    Arthritis Rheum., 2006;54(10):3182-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  145. Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.
    Authors: Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stampfli MR, Jordana M
    J. Immunol., 2006;176(4):2568-80.
    Species: Mouse
    Sample Types: Serum
  146. Long-term blockade of angiotensin AT1 receptors increases survival of obese Zucker rats.
    Authors: O&amp;amp;apos;Connor SE
    Eur. J. Pharmacol., 2006;534(1):271-9.
    Species: Mouse
    Sample Types: Plasma
  147. Integrating genetic and network analysis to characterize genes related to mouse weight.
    Authors: Ghazalpour A, Doss S, Zhang B, Wang S, Plaisier C, Castellanos R, Brozell A, Schadt EE, Drake TA, Lusis AJ, Horvath S
    PLoS Genet., 2006;2(8):e130.
    Species: Mouse
    Sample Types: Plasma
  148. Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation.
    Authors: Sergejeva S, Ivanov S, Lotvall J, Linden A
    Am. J. Respir. Cell Mol. Biol., 2005;33(3):248-53.
    Species: Mouse
    Sample Types: BALF
  149. Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion.
    Authors: Stathopoulos GT, Zhu Z, Everhart MB, Kalomenidis I, Lawson WE, Bilaceroglu S, Peterson TE, Mitchell D, Yull FE, Light RW, Blackwell TS
    Am. J. Respir. Cell Mol. Biol., 2005;34(2):142-50.
    Species: Mouse
    Sample Types: Serum
  150. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).
    Authors: Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, Bottazzi B, Doni A, Vincenzo B, Pasqualini F, Vago L, Nebuloni M, Mantovani A, Sica A
    Blood, 2005;107(5):2112-22.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  151. Antibody-bound beta-amyloid precursor protein stimulates the production of tumor necrosis factor-alpha and monocyte chemoattractant protein-1 by cortical neurons.
    Authors: Gonzalez de Aguilar JL, Dupuis L, Larmet Y
    Neurobiol. Dis., 2005;19(1):129-41.
    Species: Mouse
    Sample Types: Cell Lysates
  152. Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts.
    Authors: Tanaka M, Terry RD, Mokhtari GK, Inagaki K, Koyanagi T, Kofidis T, Mochly-Rosen D, Robbins RC
    Circulation, 2004;110(11):II194-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  153. Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.
    Authors: Koh YS, Yun JH, Seong SY, Choi MS, Kim IS
    Microb. Pathog., 2004;36(1):51-7.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  154. Role of monocyte chemotactic protein-1/CC chemokine ligand 2 on gamma delta T lymphocyte trafficking during inflammation induced by lipopolysaccharide or Mycobacterium bovis bacille Calmette-Guerin.
    Authors: Penido C, Vieira-de-Abreu A, Bozza MT, Castro-Faria-Neto HC, Bozza PT
    J. Immunol., 2003;171(12):6788-94.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  155. Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
    Authors: Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
    J. Immunol., 2002;169(6):2823-7.
    Species: Mouse
    Sample Types: Serum
  156. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
    Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
    Immunity, 2001;14(6):705-14.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  157. The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
    Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
    Eur. J. Immunol., 2001;31(7):2104-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  158. Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
    Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
    J. Immunol., 2001;166(2):1233-40.
    Species: Mouse
    Sample Types: Tissue Homogenates
  159. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
    Authors: Medvedev AE, Kopydlowski KM, Vogel SN
    J. Immunol., 2000;164(11):5564-74.
    Species: Mouse
    Sample Types: Cell Culture Supernates

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