Mouse CCR8 PE-conjugated Antibody

Recombinant Monoclonal Antibody.
(1 Review)
  • Species Reactivity
  • Specificity
    Stains mouse CCR8 transfectants but not irrelevant transfectants in flow cytometry.
  • Source
    Recombinant Monoclonal Rabbit IgG Clone # 1055C
  • Purification
    Protein A or G purified from cell culture supernatant
  • Immunogen
    HEK293 human embryonic kidney cell line transfected with mouse CCR8
    Accession # NP_031746
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of CCR8 in HEK293 Human Cell Line Transfected with Mouse CCR8 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with mouse CCR8 and eGFP (top panel) or irrelevant transfectant (bottom panel) were stained with Rabbit Anti-Mouse CCR8 PE‑conjugated Antigen Affinity-purified Monoclonal Antibody (Catalog # FAB8324P). Quadrant markers were set based on control antibody staining (Catalog # IC105P). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CCR8
CCR8 (C-C chemokine Receptor 8; also known as CD198) is a 41-43 kDa member of the GPCR #1 family of transmembrane proteins. Mouse CCR8 is expressed on vascular smooth muscle cells, monocytes, eosinophils, peritoneal macrophages, thymocytes, CD8+ T cells, Langerhans cells and neurons. CCL1/TCA3 and vMIP-1 are known agonists for CCR8. Mouse CCR8 is a 7-transmembrane protein that is 353 amino acids (aa) in length. It contains a 33 aa N-terminal extracellular domain plus a 50 aa C-terminal cytoplasmic tail. In mouse, CCR8 is N- and possibly O-glycosylated, and known to be sulfated on Tyr14 and 15. The unusual nature of these posttranslational modifications may lead to anomalous migration in SDS-PAGE. Over aa sequences 1-33 and 92-105 collectively, mouse CCR8 shares 64% and 85% aa identity with human and rat CCR8, respectively.
  • Entrez Gene IDs:
    1237 (Human); 12776 (Mouse)
  • Alternate Names:
    CC chemokine receptor 8; C-C CKR-8; CC-chemokine receptor chemr1; CC-CKR-8; CCR8; CCR-8; CD198; CDw198 antigen; CDw198; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; Chemokine receptor-like 1; ChemR1; CKRL1; CKR-L1; CKRL1MGC129966; CMKBR8MGC129973; CMKBRL2C-C chemokine receptor type 8; CY6; GPRCL1; GPRCY6; GPR-CY6; TER-1; TER1CC chemokine receptor CHEMR1
Related Research Areas
Isotype Controls
Description Application Cat# Citations Images  

Normal Rabbit IgG PE-conjugated Control

Ctrl IC105P
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Rabbit IgG PE-conjugated Antibody

Ctrl IC1051P
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Average Rating: 3 (Based on 1 review)

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We have 1 review tested in 1 species: Mouse.
We have 1 review tested in 1 application: Flow Cytometry.

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Images Ratings Applications Species Reviewed By Date Details
Flow Cytometry Mouse CCR8 PE-conjugated Antibody FAB8324p
 Flow Mouse Anonymous 08/18/2016
Image Details
Flow Cytometry Mouse CCR8 PE-conjugated Antibody FAB8324p
Flow Cytometry: Mouse CCR8 PE-conjugated Antibody [FAB8324p]


ApplicationFlow Cytometry
Sample Testedmouse splenic CD4 T

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