Mouse CysTLR2 (NP_598481) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Mouse CysTLR2 (NP_598481) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: Cysteinyl Leukotriene R2/CysLTR2

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. CysLTR2 seems to play a major role in endocrine and cardiovascular systems. Stimulation of CysLTR2 by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium.

Long Name
Cysteinyl Leukotriene Receptor 2
Entrez Gene IDs
57105 (Human); 70086 (Mouse); 170926 (Rat)
Alternate Names
CysLT(2); CysLT2; CYSLT2KPG_011; CYSLT2RHG57; CysLTR2; cysteinyl leukotriene CysLT2 receptor; Cysteinyl Leukotriene R2; cysteinyl leukotriene receptor 2; Cysteinyl LeukotrieneR2; G protein-coupled receptor; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; HG57; hGPCR21; HPN321; KPG_011


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