Mouse Erythropoietin Quantikine ELISA Kit MEP00B: R&D Systems

Mouse Erythropoietin Quantikine ELISA Kit

(64 citations)
(1 Review)
  
  • Assay Length
    4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (50 uL), Tissue Homogenates (50 uL), Serum (25 uL), Heparin Plasma (25 uL)
  • Sensitivity
    46.9 pg/mL
  • Assay Range
    47.0 - 3,000 pg/mL (Cell Culture Supernates, Tissue Homogenates, Serum, Heparin Plasma)
  • Specificity
    Natural and recombinant mouse Epo. Recombinant rat Epo has 100% cross-reactivity in this kit. This kit is not validated for use with rat samples, because rat sample dilution is not linear.
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    Interference observed with 1 or more available related molecules.
Product Summary
The Quantikine Mouse Epo Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse Epo in cell culture supernates, tissue homogenates, serum, and plasma. It contains antibodies raised against recombinant Epo and has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse Epo showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that the Quantikine Mouse Epo kit can be used to determine relative mass values for naturally occurring mouse Epo.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Cell Culture Supernates, Tissue Homogenates, Serum, Heparin Plasma
Intra-Assay Precision Inter-Assay Precision
Sample123123
n202020202020
Mean196258704180239700
Standard Deviation7.77.831.217.515.317.5
CV%3.934.49.76.42.5

Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision Inter-Assay Precision
Sample123123
n202020202020
Mean196258704180239700
Standard Deviation7.77.831.217.515.317.5
CV%3.934.49.76.42.5

Recovery

The recovery of Epo spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=7) 110 102-117
Heparin Plasma (n=8) 103 90-120
Serum (n=9) 93 85-114
Tissue Homogenates (n=3) 94 80-111
Linearity
To assess the linearity of the assay, samples containing or spiked with high concentrations of Epo in each matrix were diluted with Calibrator Diluent and then assayed.
Mouse Erythropoietin Quantikine ELISA Kit
Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: Erythropoietin
Erythropoietin (Epo) is a 30-kDa, heavily glycosylated protein produced primarily by the kidney. It is the principal factor that regulates erythropoiesis. The production of Epo by kidney cells is increased in response to hypoxia or anemia. The cDNAs for Epo have been cloned from many species. The mature proteins from the various species are highly conserved, exhibiting greater than 80% sequence identity at the amino acid level.

The biological effects of Epo are mediated by the Erythropoietin receptor (Epo R). At the protein sequence level, the human Epo R is approximately 83% identical to the mouse protein. As a result of alternative splicing of the Epo R gene, cDNA clones encoding truncated soluble forms of Epo R have been found. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

    • Entrez Gene IDs
      2056 (Human); 13856 (Mouse); 24335 (Rat);
    • Alternate Names
      EP; EPO; epoetin; Erythropoietin; MGC138142; MVCD2;
    Related Research Areas
    Citations:

    R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

    64 Citations: Showing 1 - 10
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    Species
    Sample Type
    1. Deletion of Stk40 impairs definitive erythropoiesis in the mouse fetal liver
      Authors: L Wang, H Yu, H Cheng, K He, Z Fang, L Ge, T Cheng, Y Jin
      Cell Death Dis, 2017;8(3):e2722.
      Species: Mouse
      Sample Type: Plasma
    2. Clostridium perfringens ?-toxin impairs erythropoiesis by inhibition of erythroid differentiation
      Authors: T Takagishi, M Takehara, S Seike, K Miyamoto, K Kobayashi, M Nagahama
      Sci Rep, 2017;7(1):5217.
      Species: Mouse
      Sample Type: Plasma
    3. The protective role of TET2 in erythroid iron homeostasis against oxidative stress and erythropoiesis
      Authors: S Guo, X Jiang, Y Wang, L Chen, H Li, X Li, Y Jia
      Cell. Signal., 2017;38(0):106-115.
      Species: Mouse
      Sample Type: Serum
    4. Protective effect of maternal uteroplacental insufficiency on oxygen-induced retinopathy in offspring: removing bias of premature birth
      Authors: S Becker, H Wang, B Yu, R Brown, X Han, RH Lane, ME Hartnett
      Sci Rep, 2017;7(0):42301.
      Species: Rat
      Sample Type: Serum
    5. A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-? and TGF-?1 pathways
      Authors: H Shima, K Sasaki, T Suzuki, C Mukawa, T Obara, Y Oba, A Matsuo, T Kobayashi, E Mishima, S Watanabe, Y Akiyama, K Kikuchi, T Matsuhashi, Y Oikawa, F Nanto, Y Akiyama, HJ Ho, C Suzuki, D Saigusa, A Masamune, Y Tomioka, T Masaki, S Ito, KI Hayashi, T Abe
      Sci Rep, 2017;7(1):1884.
      Species: Mouse
      Sample Type: Plasma
    6. Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors.
      Authors: Canli O, Alankus Y, Grootjans S, Vegi N, Hultner L, Hoppe P, Schroeder T, Vandenabeele P, Bornkamm G, Greten F
      Blood, 2016;127(1):139-48.
      Species: Mouse
      Sample Type: Serum
    7. Hypoxia sensing through ?-adrenergic receptors
      JCI Insight, 2016;1(21):e90240.
      Species: Mouse
      Sample Type: Serum
    8. Hypercapnia suppresses the HIF-dependent adaptive response to hypoxia
      Authors: AC Selfridge, MA Cavadas, CC Scholz, EL Campbell, LC Welch, E Lecuona, SP Colgan, KE Barrett, PH Sporn, JI Sznajder, EP Cummins, CT Taylor
      J Biol Chem, 2016;0(0):.
      Species: Mouse
      Sample Type: Serum
    9. Renal Anemia Model Mouse Established by Transgenic Rescue with Erythropoietin Gene Lacking Kidney-specific Regulatory Elements
      Mol. Cell. Biol, 2016;0(0):.
      Species: Mouse
      Sample Type: Plasma
    10. Notch downregulation and extramedullary erythrocytosis in HIF prolyl 4-hydroxylase-2-deficient mice
      Mol. Cell. Biol., 2016;0(0):.
      Species: Mouse
      Sample Type: Serum
    11. The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia
      Authors: RB Hamanaka, SE Weinberg, CR Reczek, NS Chandel
      Cell Rep, 2016;15(3):451-9.
      Species: Mouse
      Sample Type: Serum
    12. Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice
      Stem Cell Reports, 2016;0(0):.
      Species: Mouse
      Sample Type: Plasma
    13. Human CD133(+) Renal Progenitor Cells Induce Erythropoietin Production and Limit Fibrosis After Acute Tubular Injury
      Sci Rep, 2016;6(0):37270.
      Species: Mouse
      Sample Type: Plasma
    14. The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 is Essential for Efficient Hydroxylation of Hypoxia Inducible Factor-?
      Authors: Patrick R Arsenault
      Mol Cell Biol, 2016;0(0):.
      Species: Mouse
      Sample Type: Serum
    15. Salmonella infection enhances erythropoietin production by the kidney and liver correlating with elevated bacterial burdens
      Infect Immun, 2016;0(0):.
      Species: Mouse
      Sample Type: Serum
    16. Phagocyte respiratory burst activates macrophage erythropoietin signalling to promote acute inflammation resolution
      Nat Commun, 2016;7(0):12177.
      Species: Mouse
      Sample Type: Peritoneal Fluid
    17. Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis
      Authors: T Kamio, BW Gu, TS Olson, Y Zhang, PJ Mason, M Bessler
      PLoS ONE, 2016;11(4):e0152263.
      Species: Mouse
      Sample Type: Serum
    18. Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity
      Authors: G Hoppe, S Yoon, B Gopalan, AR Savage, R Brown, K Case, A Vasanji, ER Chan, RB Silver, JE Sears
      Proc Natl Acad Sci USA, 2016;0(0):.
      Species: Mouse
      Sample Type: Serum
    19. Rasa3 controls megakaryocyte Rap1 activation, integrin signaling and differentiation into proplatelet.
      Authors: Molina-Ortiz P, Polizzi S, Ramery E, Gayral S, Delierneux C, Oury C, Iwashita S, Schurmans S
      PLoS Genet, 2014;10(6):e1004420.
      Species: Mouse
      Sample Type: Serum
    20. Mimicking hypoxia to treat anemia: HIF-stabilizer BAY 85-3934 (Molidustat) stimulates erythropoietin production without hypertensive effects.
      Authors: Flamme I, Oehme F, Ellinghaus P, Jeske M, Keldenich J, Thuss U
      PLoS ONE, 2014;9(11):e111838.
      Species: Rat
      Sample Type: Plasma
    21. An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin.
      Authors: Carrancio S, Markovics J, Wong P, Leisten J, Castiglioni P, Groza M, Raymon H, Heise C, Daniel T, Chopra R, Sung V
      Br J Haematol, 2014;165(6):870-82.
      Species: Mouse
      Sample Type: Plasma
    22. Chronic psychological stress activates BMP4-dependent extramedullary erythropoiesis.
      Authors: Vignjevic S, Budec M, Markovic D, Dikic D, Mitrovic O, Mojsilovic S, Duric S, Koko V, Cokic B, Cokic V, Jovcic G
      J Cell Mol Med, 2014;18(1):91-103.
      Species: Mouse
      Sample Type: Plasma
    23. Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate.
      Authors: Grover, Amit, Mancini, Elena, Moore, Susan, Mead, Adam J, Atkinson, Deborah, Rasmussen, Kasper D, O'Carroll, Donal, Jacobsen, Sten Eir, Nerlov, Claus
      J Exp Med, 2014;211(2):181-8.
      Species: Mouse
      Sample Type: Serum
    24. Transgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primates.
      Authors: Le Guiner C, Stieger K, Toromanoff A, Guilbaud M, Mendes-Madeira A, Devaux M, Guigand L, Cherel Y, Moullier P, Rolling F, Adjali O
      PLoS ONE, 2014;9(9):e102538.
      Species: Mouse
      Sample Type: Serum
    25. Inducing a visceral organ to protect a peripheral capillary bed: stabilizing hepatic HIF-1alpha prevents oxygen-induced retinopathy.
      Authors: Hoppe G, Lee T, Yoon S, Yu M, Peachey N, Rayborn M, Zutel M, Trichonas G, Au J, Sears J
      Am J Pathol, 2014;184(6):1890-9.
      Species: Mouse
      Sample Type: Serum
    26. Klotho deficiency disrupts hematopoietic stem cell development and erythropoiesis.
      Authors: Vadakke Madathil S, Coe L, Casu C, Sitara D
      Am J Pathol, 2014;184(3):827-41.
      Species: Mouse
      Sample Type: Serum
    27. The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice.
      Authors: Nai A, Pellegrino R, Rausa M, Pagani A, Boero M, Silvestri L, Saglio G, Roetto A, Camaschella C
      Haematologica, 2014;99(6):1016-21.
      Species: Mouse
      Sample Type: Serum
    28. FGF-23 is a negative regulator of prenatal and postnatal erythropoiesis.
      Authors: Coe, Lindsay, Madathil, Sangeeth, Casu, Carla, Lanske, Beate, Rivella, Stefano, Sitara, Despina
      J Biol Chem, 2014;289(14):9795-810.
      Species: Mouse
      Sample Type: Serum
    29. Ciprofloxacin enhances stress erythropoiesis in spleen and increases survival after whole-body irradiation combined with skin-wound trauma.
      Authors: Fukumoto R, Burns T, Kiang J
      PLoS ONE, 2014;9(2):e90448.
      Species: Mouse
      Sample Type: Serum
    30. Conditional disruption of the prolyl hydroxylase domain-containing protein 2 (Phd2) gene defines its key role in skeletal development.
      Authors: Cheng S, Xing W, Pourteymoor S, Mohan S
      J Bone Miner Res, 2014;29(10):2276-86.
      Species: Mouse
      Sample Type: Serum
    31. An activin receptor IIA ligand trap corrects ineffective erythropoiesis in beta-thalassemia.
      Authors: Dussiot M, Maciel T, Fricot A, Chartier C, Negre O, Veiga J, Grapton D, Paubelle E, Payen E, Beuzard Y, Leboulch P, Ribeil J, Arlet J, Cote F, Courtois G, Ginzburg Y, Daniel T, Chopra R, Sung V, Hermine O, Moura I
      Nat Med, 2014;20(4):398-407.
      Species: Mouse
      Sample Type: Serum
    32. A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficiency mechanism.
      Authors: Arsenault, Patrick, Pei, Fei, Lee, Rebecca, Kerestes, Heddy, Percy, Melanie, Keith, Brian, Simon, M Celest, Lappin, Terence, Khurana, Tejvir S, Lee, Frank S
      J Biol Chem, 2013;288(47):33571-84.
      Species: Mouse
      Sample Type: Serum
    33. Impaired in vitro erythropoiesis following deletion of the Scl (Tal1) +40 enhancer is largely compensated for in vivo despite a significant reduction in expression.
      Authors: Ferreira R, Spensberger D, Silber Y, Dimond A, Li J, Green A, Gottgens B
      Mol Cell Biol, 2013;33(6):1254-66.
      Species: Mouse
      Sample Type: Serum
    34. EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress.
      Authors: Peslak, Scott A, Wenger, Jesse, Bemis, Jeffrey, Kingsley, Paul D, Koniski, Anne D, McGrath, Kathleen, Palis, James
      Blood, 2012;120(12):2501-11.
      Species: Mouse
      Sample Type: Plasma
    35. Treatment of erythropoietin deficiency in mice with systemically administered siRNA.
      Authors: Querbes, William, Bogorad, Roman L, Moslehi, Javid, Wong, Jamie, Chan, Amy Y, Bulgakova, Elena, Kuchimanchi, Satya, Akinc, Akin, Fitzgerald, Kevin, Koteliansky, Victor, Kaelin, William
      Blood, 2012;120(9):1916-22.
      Species: Mouse
      Sample Type: Serum
    36. Exogenous erythropoietin administration attenuates intermittent hypoxia-induced cognitive deficits in a murine model of sleep apnea.
      BMC Neurosci, 2012;13(0):77.
      Species: Mouse
      Sample Type: Tissue Homogenates
    37. 3'UTR-truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growth advantage at the level of HSC in mice.
      Authors: Ikeda K, Mason PJ, Bessler M
      Blood, 2011;117(22):5860-9.
      Species: Mouse
      Sample Type: Serum
    38. Aconitase Regulation of Erythropoiesis Correlates with a Novel Licensing Function in Erythropoietin-Induced ERK Signaling.
      Authors: Talbot AL, Bullock GC, Delehanty LL
      PLoS ONE, 2011;6(8):e23850.
      Species: Mouse
      Sample Type: Serum
    39. A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency.
      Authors: Salojin KV, Cabrera RM, Sun W
      Blood, 2011;117(18):4895-904.
      Species: Mouse
      Sample Type: Serum
    40. Minimal doses of a sequence-optimized transgene mediate high-level and long-term EPO expression in vivo: challenging CpG-free gene design.
      Authors: Kosovac D, Wild J, Ludwig C, Meissner S, Bauer AP, Wagner R
      Gene Ther., 2011;18(2):189-98.
      Species: Mouse
      Sample Type: Serum
    41. A postweaning iron-adequate diet following neonatal iron deficiency affects iron homeostasis and growth in young rats.
      Authors: Hegde NV, Jensen GL, Unger EL
      J. Nutr., 2011;141(3):386-90.
      Species: Rat
      Sample Type: Serum
    42. General anesthetics inhibit erythropoietin induction under hypoxic conditions in the mouse brain.
      Authors: Tanaka T, Kai S, Koyama T, Daijo H, Adachi T, Fukuda K, Hirota K
      PLoS ONE, 2011;6(12):e29378.
      Species: Mouse
      Sample Type: Tissue Homogenates
    43. Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly.
      Authors: Jackson A, Nanton MR, O'Donnell H
      J. Immunol., 2010;185(10):6198-204.
      Species: Mouse
      Sample Type: Serum
    44. Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection.
      Authors: Morrison LJ, McLellan S, Sweeney L, Chan CN, MacLeod A, Tait A, Turner CM
      Infect. Immun., 2010;78(3):1096-108.
      Species: Mouse
      Sample Type: Plasma
    45. Cellular and molecular mechanisms regulating the hepatic erythropoietin expression during acute-phase response: a role for IL-6.
      Authors: Ramadori P, Ahmad G, Ramadori G
      Lab. Invest., 2010;90(9):1306-24.
      Species: Mouse
      Sample Type: Serum
    46. JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia.
      Authors: Li J, Spensberger D, Ahn JS
      Blood, 2010;116(9):1528-38.
      Species: Mouse
      Sample Type: Plasma
    47. AMPKalpha1 deletion shortens erythrocyte life span in mice: role of oxidative stress.
      Authors: Wang S, Dale GL, Song P
      J. Biol. Chem., 2010;285(26):19976-85.
      Species: Mouse
      Sample Type: Plasma
    48. Therapeutic levels of erythropoietin (EPO) achieved after gene electrotransfer to skin in mice.
      Authors: Gothelf A, Hojman P, Gehl J
      Gene Ther., 2010;17(9):1077-84.
      Species: Mouse
      Sample Type: Serum
    49. Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain.
      Authors: Schneider C, Krischke G, Keller S, Walkinshaw G, Arend M, Rascher W, Gassmann M, Trollmann R
      Brain Res., 2009;1280(0):43-51.
      Species: Mouse
      Sample Type: Serum
    50. Hyperoxia disrupts vascular endothelial growth factor-nitric oxide signaling and decreases growth of endothelial colony-forming cells from preterm infants.
      Authors: Fujinaga H, Baker CD, Ryan SL, Markham NE, Seedorf GJ, Balasubramaniam V, Abman SH
      Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(6):L1160-9.
      Species: Mouse
      Sample Type: Serum
    51. The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.
      Authors: Weidemann A, Kerdiles YM, Knaup KX, Rafie CA, Boutin AT, Stockmann C, Takeda N, Scadeng M, Shih AY, Haase VH, Simon MC, Kleinfeld D, Johnson RS
      J. Clin. Invest., 2009;119(11):3373-83.
      Species: Mouse
      Sample Type: Plasma
    52. HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.
      Authors: Mastrogiannaki M, Matak P, Keith B, Simon MC, Vaulont S, Peyssonnaux C
      J. Clin. Invest., 2009;119(5):1159-66.
      Species: Mouse
      Sample Type: Serum
    53. Rescue of pyruvate kinase deficiency in mice by gene therapy using the human isoenzyme.
      Authors: Meza NW, Alonso-Ferrero ME, Navarro S, Quintana-Bustamante O, Valeri A, Garcia-Gomez M, Bueren JA, Bautista JM, Segovia JC
      Mol. Ther., 2009;17(12):2000-9.
      Species: Mouse
      Sample Type: Plasma
    54. Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice.
      Authors: Xing S, Wanting TH, Zhao W, Ma J, Wang S, Xu X, Li Q, Fu X, Xu M, Zhao ZJ
      Blood, 2008;111(10):5109-17.
      Species: Mouse
      Sample Type: Plasma
    55. Epidermal sensing of oxygen is essential for systemic hypoxic response.
      Authors: Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, Johnson RS
      Cell, 2008;133(2):223-34.
      Species: Mouse
      Sample Type: Plasma
    56. n-Propyl gallate activates hypoxia-inducible factor 1 by modulating intracellular oxygen-sensing systems.
      Authors: Kimura M, Takabuchi S, Tanaka T, Murata M, Nishi K, Oda S, Oda T, Kanai M, Fukuda K, Kizaka-Kondoh S, Adachi T, Takabayashi A, Semenza GL, Hirota K
      Biochem. J., 2008;411(1):97-105.
      Species: Mouse
      Sample Type: Serum
    57. Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.
      Authors: Kerenyi MA, Grebien F, Gehart H, Schifrer M, Artaker M, Kovacic B, Beug H, Moriggl R, Mullner EW
      Blood, 2008;112(9):3878-88.
      Species: Mouse
      Sample Type: Serum
    58. Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy.
      Authors: Ebos JM, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS
      Proc. Natl. Acad. Sci. U.S.A., 2007;104(43):17069-74.
      Species: Mouse
      Sample Type: Plasma
    59. von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
      Authors: Hickey MM, Lam JC, Bezman NA, Rathmell WK, Simon MC
      J. Clin. Invest., 2007;117(12):3879-3889.
      Species: Mouse
      Sample Type: Serum
    60. Microcytosis in ank/ank mice and the role of ANKH in promoting erythroid differentiation.
      Authors: Wang J, Wang C, Tsui HW, Las Heras F, Cheng EY, Iscove NN, Chiu B, Inman RD, Pritzker KP, Tsui FW
      Exp. Cell Res., 2007;313(20):4120-9.
      Species: Mouse
      Sample Type: Serum
    61. Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice.
      Authors: Tiedt R, Hao-Shen H, Sobas MA, Looser R, Dirnhofer S, Schwaller J, Skoda RC
      Blood, 2007;111(8):3931-40.
      Species: Mouse
      Sample Type: Plasma
    62. Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
      Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
      Am. J. Pathol., 2007;170(3):1003-17.
      Species: Mouse
      Sample Type: Tissue Homogenates
    63. Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo.
      Authors: Braun BS, Archard JA, Van Ziffle JA, Tuveson DA, Jacks TE, Shannon K
      Blood, 2006;108(6):2041-4.
      Species: Mouse
      Sample Type: Serum
    64. Suppression of hepcidin during anemia requires erythropoietic activity.
      Authors: Pak M, Lopez MA, Gabayan V, Ganz T, Rivera S
      Blood, 2006;108(12):3730-5.
      Species: Mouse
      Sample Type: Serum
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