Mouse Erythropoietin Quantikine ELISA Kit

  (67 citations)
(3 Reviews)
    
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Product Details
Citations (67)
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  • Assay Length
    4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (50 uL), Tissue Homogenates (50 uL), Serum (25 uL), Heparin Plasma (25 uL)
  • Sensitivity
    46.9 pg/mL
  • Assay Range
    47.0 - 3,000 pg/mL (Cell Culture Supernates, Tissue Homogenates, Serum, Heparin Plasma)
  • Specificity
    Natural and recombinant mouse Epo. Recombinant rat Epo has 100% cross-reactivity in this kit. This kit is not validated for use with rat samples, because rat sample dilution is not linear.
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    Interference observed with 1 or more available related molecules.
Product Summary
The Quantikine Mouse Epo Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse Epo in cell culture supernates, tissue homogenates, serum, and plasma. It contains antibodies raised against recombinant Epo and has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse Epo showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that the Quantikine Mouse Epo kit can be used to determine relative mass values for naturally occurring mouse Epo.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates, Tissue Homogenates, Serum, Heparin Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 196 258 704 180 239 700
Standard Deviation 7.7 7.8 31.2 17.5 15.3 17.5
CV% 3.9 3 4.4 9.7 6.4 2.5

Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 196 258 704 180 239 700
Standard Deviation 7.7 7.8 31.2 17.5 15.3 17.5
CV% 3.9 3 4.4 9.7 6.4 2.5

Recovery

The recovery of Epo spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=7) 110 102-117
Heparin Plasma (n=8) 103 90-120
Serum (n=9) 93 85-114
Tissue Homogenates (n=3) 94 80-111
Linearity
To assess the linearity of the assay, samples containing or spiked with high concentrations of Epo in each matrix were diluted with Calibrator Diluent and then assayed.
 Erythropoietin [HRP]
Product Datasheets

Certificate of Analysis Lookup

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Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: Erythropoietin
Erythropoietin (Epo) is a 30-kDa, heavily glycosylated protein produced primarily by the kidney. It is the principal factor that regulates erythropoiesis. The production of Epo by kidney cells is increased in response to hypoxia or anemia. The cDNAs for Epo have been cloned from many species. The mature proteins from the various species are highly conserved, exhibiting greater than 80% sequence identity at the amino acid level.

The biological effects of Epo are mediated by the Erythropoietin receptor (Epo R). At the protein sequence level, the human Epo R is approximately 83% identical to the mouse protein. As a result of alternative splicing of the Epo R gene, cDNA clones encoding truncated soluble forms of Epo R have been found. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

  • Entrez Gene IDs:
    2056 (Human); 13856 (Mouse); 24335 (Rat)
  • Alternate Names:
    EP; EPO; epoetin; Erythropoietin; MGC138142; MVCD2
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

67 Citations: Showing 1 - 10
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Species
Sample Type
  1. Iron suppresses erythropoietin expression via oxidative stress-dependent hypoxia-inducible factor-2 alpha inactivation
    Authors: K Oshima, Y Ikeda, Y Horinouchi, H Watanabe, H Hamano, Y Kihira, S Kishi, Y Izawa-Ishi, L Miyamoto, T Hirayama, H Nagasawa, K Ishizawa, K Tsuchiya, T Tamaki
    Lab. Invest, 2017;0(0):.
    Species: Mouse
    Sample Type: Plasma
  2. The protective role of TET2 in erythroid iron homeostasis against oxidative stress and erythropoiesis
    Authors: S Guo, X Jiang, Y Wang, L Chen, H Li, X Li, Y Jia
    Cell. Signal., 2017;38(0):106-115.
    Species: Mouse
    Sample Type: Serum
  3. Deletion of Stk40 impairs definitive erythropoiesis in the mouse fetal liver
    Authors: L Wang, H Yu, H Cheng, K He, Z Fang, L Ge, T Cheng, Y Jin
    Cell Death Dis, 2017;8(3):e2722.
    Species: Mouse
    Sample Type: Plasma
  4. A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-? and TGF-?1 pathways
    Authors: H Shima, K Sasaki, T Suzuki, C Mukawa, T Obara, Y Oba, A Matsuo, T Kobayashi, E Mishima, S Watanabe, Y Akiyama, K Kikuchi, T Matsuhashi, Y Oikawa, F Nanto, Y Akiyama, HJ Ho, C Suzuki, D Saigusa, A Masamune, Y Tomioka, T Masaki, S Ito, KI Hayashi, T Abe
    Sci Rep, 2017;7(1):1884.
    Species: Mouse
    Sample Type: Plasma
  5. Protective effect of maternal uteroplacental insufficiency on oxygen-induced retinopathy in offspring: removing bias of premature birth
    Authors: S Becker, H Wang, B Yu, R Brown, X Han, RH Lane, ME Hartnett
    Sci Rep, 2017;7(0):42301.
    Species: Rat
    Sample Type: Serum
  6. Clostridium perfringens ?-toxin impairs erythropoiesis by inhibition of erythroid differentiation
    Authors: T Takagishi, M Takehara, S Seike, K Miyamoto, K Kobayashi, M Nagahama
    Sci Rep, 2017;7(1):5217.
    Species: Mouse
    Sample Type: Plasma
  7. FGF23 expression in rodents is directly induced via erythropoietin after inhibition of hypoxia inducible factor proline hydroxylase
    Authors: I Flamme, P Ellinghaus, D Urrego, T Krüger
    PLoS ONE, 2017;12(10):e0186979.
    Species: Rat
    Sample Type: Plasma
  8. Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of spontaneous breast cancer
    Authors: TW Seeley, MD Sternlicht, SJ Klaus, TB Neff, DY Liu
    Hypoxia (Auckl), 2017;5(0):1-9.
    Species: Mouse
    Sample Type: Plasma
  9. Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors.
    Authors: Canli O, Alankus Y, Grootjans S, Vegi N, Hultner L, Hoppe P, Schroeder T, Vandenabeele P, Bornkamm G, Greten F
    Blood, 2016;127(1):139-48.
    Species: Mouse
    Sample Type: Serum
  10. Hypercapnia suppresses the HIF-dependent adaptive response to hypoxia
    Authors: AC Selfridge, MA Cavadas, CC Scholz, EL Campbell, LC Welch, E Lecuona, SP Colgan, KE Barrett, PH Sporn, JI Sznajder, EP Cummins, CT Taylor
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Type: Serum
  11. The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia
    Authors: RB Hamanaka, SE Weinberg, CR Reczek, NS Chandel
    Cell Rep, 2016;15(3):451-9.
    Species: Mouse
    Sample Type: Serum
  12. The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 is Essential for Efficient Hydroxylation of Hypoxia Inducible Factor-?
    Authors: Patrick R Arsenault
    Mol Cell Biol, 2016;0(0):.
    Species: Mouse
    Sample Type: Serum
  13. Phagocyte respiratory burst activates macrophage erythropoietin signalling to promote acute inflammation resolution
    Nat Commun, 2016;7(0):12177.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  14. Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity
    Authors: G Hoppe, S Yoon, B Gopalan, AR Savage, R Brown, K Case, A Vasanji, ER Chan, RB Silver, JE Sears
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Mouse
    Sample Type: Serum
  15. Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis
    Authors: T Kamio, BW Gu, TS Olson, Y Zhang, PJ Mason, M Bessler
    PLoS ONE, 2016;11(4):e0152263.
    Species: Mouse
    Sample Type: Serum
  16. Salmonella infection enhances erythropoietin production by the kidney and liver correlating with elevated bacterial burdens
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Type: Serum
  17. Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice
    Stem Cell Reports, 2016;0(0):.
    Species: Mouse
    Sample Type: Plasma
  18. Human CD133(+) Renal Progenitor Cells Induce Erythropoietin Production and Limit Fibrosis After Acute Tubular Injury
    Sci Rep, 2016;6(0):37270.
    Species: Mouse
    Sample Type: Plasma
  19. Notch downregulation and extramedullary erythrocytosis in HIF prolyl 4-hydroxylase-2-deficient mice
    Mol. Cell. Biol., 2016;0(0):.
    Species: Mouse
    Sample Type: Serum
  20. Renal Anemia Model Mouse Established by Transgenic Rescue with Erythropoietin Gene Lacking Kidney-specific Regulatory Elements
    Mol. Cell. Biol, 2016;0(0):.
    Species: Mouse
    Sample Type: Plasma
  21. Hypoxia sensing through ?-adrenergic receptors
    JCI Insight, 2016;1(21):e90240.
    Species: Mouse
    Sample Type: Serum
  22. Chronic psychological stress activates BMP4-dependent extramedullary erythropoiesis.
    Authors: Vignjevic S, Budec M, Markovic D, Dikic D, Mitrovic O, Mojsilovic S, Duric S, Koko V, Cokic B, Cokic V, Jovcic G
    J Cell Mol Med, 2014;18(1):91-103.
    Species: Mouse
    Sample Type: Plasma
  23. Transgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primates.
    Authors: Le Guiner C, Stieger K, Toromanoff A, Guilbaud M, Mendes-Madeira A, Devaux M, Guigand L, Cherel Y, Moullier P, Rolling F, Adjali O
    PLoS ONE, 2014;9(9):e102538.
    Species: Mouse
    Sample Type: Serum
  24. Rasa3 controls megakaryocyte Rap1 activation, integrin signaling and differentiation into proplatelet.
    Authors: Molina-Ortiz P, Polizzi S, Ramery E, Gayral S, Delierneux C, Oury C, Iwashita S, Schurmans S
    PLoS Genet, 2014;10(6):e1004420.
    Species: Mouse
    Sample Type: Serum
  25. Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate.
    Authors: Grover, Amit, Mancini, Elena, Moore, Susan, Mead, Adam J, Atkinson, Deborah, Rasmussen, Kasper D, O'Carroll, Donal, Jacobsen, Sten Eir, Nerlov, Claus
    J Exp Med, 2014;211(2):181-8.
    Species: Mouse
    Sample Type: Serum
  26. FGF-23 is a negative regulator of prenatal and postnatal erythropoiesis.
    Authors: Coe, Lindsay, Madathil, Sangeeth, Casu, Carla, Lanske, Beate, Rivella, Stefano, Sitara, Despina
    J Biol Chem, 2014;289(14):9795-810.
    Species: Mouse
    Sample Type: Serum
  27. An activin receptor IIA ligand trap corrects ineffective erythropoiesis in beta-thalassemia.
    Authors: Dussiot M, Maciel T, Fricot A, Chartier C, Negre O, Veiga J, Grapton D, Paubelle E, Payen E, Beuzard Y, Leboulch P, Ribeil J, Arlet J, Cote F, Courtois G, Ginzburg Y, Daniel T, Chopra R, Sung V, Hermine O, Moura I
    Nat Med, 2014;20(4):398-407.
    Species: Mouse
    Sample Type: Serum
  28. The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice.
    Authors: Nai A, Pellegrino R, Rausa M, Pagani A, Boero M, Silvestri L, Saglio G, Roetto A, Camaschella C
    Haematologica, 2014;99(6):1016-21.
    Species: Mouse
    Sample Type: Serum
  29. Conditional disruption of the prolyl hydroxylase domain-containing protein 2 (Phd2) gene defines its key role in skeletal development.
    Authors: Cheng S, Xing W, Pourteymoor S, Mohan S
    J Bone Miner Res, 2014;29(10):2276-86.
    Species: Mouse
    Sample Type: Serum
  30. Ciprofloxacin enhances stress erythropoiesis in spleen and increases survival after whole-body irradiation combined with skin-wound trauma.
    Authors: Fukumoto R, Burns T, Kiang J
    PLoS ONE, 2014;9(2):e90448.
    Species: Mouse
    Sample Type: Serum
  31. An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin.
    Authors: Carrancio S, Markovics J, Wong P, Leisten J, Castiglioni P, Groza M, Raymon H, Heise C, Daniel T, Chopra R, Sung V
    Br J Haematol, 2014;165(6):870-82.
    Species: Mouse
    Sample Type: Plasma
  32. Mimicking hypoxia to treat anemia: HIF-stabilizer BAY 85-3934 (Molidustat) stimulates erythropoietin production without hypertensive effects.
    Authors: Flamme I, Oehme F, Ellinghaus P, Jeske M, Keldenich J, Thuss U
    PLoS ONE, 2014;9(11):e111838.
    Species: Rat
    Sample Type: Plasma
  33. Klotho deficiency disrupts hematopoietic stem cell development and erythropoiesis.
    Authors: Vadakke Madathil S, Coe L, Casu C, Sitara D
    Am J Pathol, 2014;184(3):827-41.
    Species: Mouse
    Sample Type: Serum
  34. Inducing a visceral organ to protect a peripheral capillary bed: stabilizing hepatic HIF-1alpha prevents oxygen-induced retinopathy.
    Authors: Hoppe G, Lee T, Yoon S, Yu M, Peachey N, Rayborn M, Zutel M, Trichonas G, Au J, Sears J
    Am J Pathol, 2014;184(6):1890-9.
    Species: Mouse
    Sample Type: Serum
  35. A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficiency mechanism.
    Authors: Arsenault, Patrick, Pei, Fei, Lee, Rebecca, Kerestes, Heddy, Percy, Melanie, Keith, Brian, Simon, M Celest, Lappin, Terence, Khurana, Tejvir S, Lee, Frank S
    J Biol Chem, 2013;288(47):33571-84.
    Species: Mouse
    Sample Type: Serum
  36. Impaired in vitro erythropoiesis following deletion of the Scl (Tal1) +40 enhancer is largely compensated for in vivo despite a significant reduction in expression.
    Authors: Ferreira R, Spensberger D, Silber Y, Dimond A, Li J, Green A, Gottgens B
    Mol Cell Biol, 2013;33(6):1254-66.
    Species: Mouse
    Sample Type: Serum
  37. Exogenous erythropoietin administration attenuates intermittent hypoxia-induced cognitive deficits in a murine model of sleep apnea.
    BMC Neurosci, 2012;13(0):77.
    Species: Mouse
    Sample Type: Tissue Homogenates
  38. Treatment of erythropoietin deficiency in mice with systemically administered siRNA.
    Authors: Querbes, William, Bogorad, Roman L, Moslehi, Javid, Wong, Jamie, Chan, Amy Y, Bulgakova, Elena, Kuchimanchi, Satya, Akinc, Akin, Fitzgerald, Kevin, Koteliansky, Victor, Kaelin, William
    Blood, 2012;120(9):1916-22.
    Species: Mouse
    Sample Type: Serum
  39. EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress.
    Authors: Peslak, Scott A, Wenger, Jesse, Bemis, Jeffrey, Kingsley, Paul D, Koniski, Anne D, McGrath, Kathleen, Palis, James
    Blood, 2012;120(12):2501-11.
    Species: Mouse
    Sample Type: Plasma
  40. 3'UTR-truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growth advantage at the level of HSC in mice.
    Authors: Ikeda K, Mason PJ, Bessler M
    Blood, 2011;117(22):5860-9.
    Species: Mouse
    Sample Type: Serum
  41. A postweaning iron-adequate diet following neonatal iron deficiency affects iron homeostasis and growth in young rats.
    Authors: Hegde NV, Jensen GL, Unger EL
    J. Nutr., 2011;141(3):386-90.
    Species: Rat
    Sample Type: Serum
  42. General anesthetics inhibit erythropoietin induction under hypoxic conditions in the mouse brain.
    Authors: Tanaka T, Kai S, Koyama T, Daijo H, Adachi T, Fukuda K, Hirota K
    PLoS ONE, 2011;6(12):e29378.
    Species: Mouse
    Sample Type: Tissue Homogenates
  43. Aconitase Regulation of Erythropoiesis Correlates with a Novel Licensing Function in Erythropoietin-Induced ERK Signaling.
    Authors: Talbot AL, Bullock GC, Delehanty LL
    PLoS ONE, 2011;6(8):e23850.
    Species: Mouse
    Sample Type: Serum
  44. A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency.
    Authors: Salojin KV, Cabrera RM, Sun W
    Blood, 2011;117(18):4895-904.
    Species: Mouse
    Sample Type: Serum
  45. Minimal doses of a sequence-optimized transgene mediate high-level and long-term EPO expression in vivo: challenging CpG-free gene design.
    Authors: Kosovac D, Wild J, Ludwig C, Meissner S, Bauer AP, Wagner R
    Gene Ther., 2011;18(2):189-98.
    Species: Mouse
    Sample Type: Serum
  46. AMPKalpha1 deletion shortens erythrocyte life span in mice: role of oxidative stress.
    Authors: Wang S, Dale GL, Song P
    J. Biol. Chem., 2010;285(26):19976-85.
    Species: Mouse
    Sample Type: Plasma
  47. Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection.
    Authors: Morrison LJ, McLellan S, Sweeney L, Chan CN, MacLeod A, Tait A, Turner CM
    Infect. Immun., 2010;78(3):1096-108.
    Species: Mouse
    Sample Type: Plasma
  48. Therapeutic levels of erythropoietin (EPO) achieved after gene electrotransfer to skin in mice.
    Authors: Gothelf A, Hojman P, Gehl J
    Gene Ther., 2010;17(9):1077-84.
    Species: Mouse
    Sample Type: Serum
  49. Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly.
    Authors: Jackson A, Nanton MR, O'Donnell H
    J. Immunol., 2010;185(10):6198-204.
    Species: Mouse
    Sample Type: Serum
  50. Cellular and molecular mechanisms regulating the hepatic erythropoietin expression during acute-phase response: a role for IL-6.
    Authors: Ramadori P, Ahmad G, Ramadori G
    Lab. Invest., 2010;90(9):1306-24.
    Species: Mouse
    Sample Type: Serum
  51. JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia.
    Authors: Li J, Spensberger D, Ahn JS
    Blood, 2010;116(9):1528-38.
    Species: Mouse
    Sample Type: Plasma
  52. Hyperoxia disrupts vascular endothelial growth factor-nitric oxide signaling and decreases growth of endothelial colony-forming cells from preterm infants.
    Authors: Fujinaga H, Baker CD, Ryan SL, Markham NE, Seedorf GJ, Balasubramaniam V, Abman SH
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(6):L1160-9.
    Species: Mouse
    Sample Type: Serum
  53. Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain.
    Authors: Schneider C, Krischke G, Keller S, Walkinshaw G, Arend M, Rascher W, Gassmann M, Trollmann R
    Brain Res., 2009;1280(0):43-51.
    Species: Mouse
    Sample Type: Serum
  54. The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.
    Authors: Weidemann A, Kerdiles YM, Knaup KX, Rafie CA, Boutin AT, Stockmann C, Takeda N, Scadeng M, Shih AY, Haase VH, Simon MC, Kleinfeld D, Johnson RS
    J. Clin. Invest., 2009;119(11):3373-83.
    Species: Mouse
    Sample Type: Plasma
  55. HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.
    Authors: Mastrogiannaki M, Matak P, Keith B, Simon MC, Vaulont S, Peyssonnaux C
    J. Clin. Invest., 2009;119(5):1159-66.
    Species: Mouse
    Sample Type: Serum
  56. Rescue of pyruvate kinase deficiency in mice by gene therapy using the human isoenzyme.
    Authors: Meza NW, Alonso-Ferrero ME, Navarro S, Quintana-Bustamante O, Valeri A, Garcia-Gomez M, Bueren JA, Bautista JM, Segovia JC
    Mol. Ther., 2009;17(12):2000-9.
    Species: Mouse
    Sample Type: Plasma
  57. Epidermal sensing of oxygen is essential for systemic hypoxic response.
    Authors: Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, Johnson RS
    Cell, 2008;133(2):223-34.
    Species: Mouse
    Sample Type: Plasma
  58. n-Propyl gallate activates hypoxia-inducible factor 1 by modulating intracellular oxygen-sensing systems.
    Authors: Kimura M, Takabuchi S, Tanaka T, Murata M, Nishi K, Oda S, Oda T, Kanai M, Fukuda K, Kizaka-Kondoh S, Adachi T, Takabayashi A, Semenza GL, Hirota K
    Biochem. J., 2008;411(1):97-105.
    Species: Mouse
    Sample Type: Serum
  59. Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice.
    Authors: Xing S, Wanting TH, Zhao W, Ma J, Wang S, Xu X, Li Q, Fu X, Xu M, Zhao ZJ
    Blood, 2008;111(10):5109-17.
    Species: Mouse
    Sample Type: Plasma
  60. Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.
    Authors: Kerenyi MA, Grebien F, Gehart H, Schifrer M, Artaker M, Kovacic B, Beug H, Moriggl R, Mullner EW
    Blood, 2008;112(9):3878-88.
    Species: Mouse
    Sample Type: Serum
  61. Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice.
    Authors: Tiedt R, Hao-Shen H, Sobas MA, Looser R, Dirnhofer S, Schwaller J, Skoda RC
    Blood, 2007;111(8):3931-40.
    Species: Mouse
    Sample Type: Plasma
  62. Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
    Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
    Am. J. Pathol., 2007;170(3):1003-17.
    Species: Mouse
    Sample Type: Tissue Homogenates
  63. Microcytosis in ank/ank mice and the role of ANKH in promoting erythroid differentiation.
    Authors: Wang J, Wang C, Tsui HW, Las Heras F, Cheng EY, Iscove NN, Chiu B, Inman RD, Pritzker KP, Tsui FW
    Exp. Cell Res., 2007;313(20):4120-9.
    Species: Mouse
    Sample Type: Serum
  64. von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
    Authors: Hickey MM, Lam JC, Bezman NA, Rathmell WK, Simon MC
    J. Clin. Invest., 2007;117(12):3879-3889.
    Species: Mouse
    Sample Type: Serum
  65. Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy.
    Authors: Ebos JM, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS
    Proc. Natl. Acad. Sci. U.S.A., 2007;104(43):17069-74.
    Species: Mouse
    Sample Type: Plasma
  66. Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo.
    Authors: Braun BS, Archard JA, Van Ziffle JA, Tuveson DA, Jacks TE, Shannon K
    Blood, 2006;108(6):2041-4.
    Species: Mouse
    Sample Type: Serum
  67. Suppression of hepcidin during anemia requires erythropoietic activity.
    Authors: Pak M, Lopez MA, Gabayan V, Ganz T, Rivera S
    Blood, 2006;108(12):3730-5.
    Species: Mouse
    Sample Type: Serum
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