Mouse ESAM Alexa Fluor® 700-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: ESAM

ESAM (Endothelial Cell-Specific Adhesion Molecule) is a 55 kDa type I transmembrane glycoprotein belonging to the CTX (cortical thymocyte marker in Xenopus) family of cell adhesion molecules within the immunoglobulin superfamily. Other family members are CXADR, CLMP, JAM-A-C, CD2, A33, and BT-IgSF. The extracellular region of ESAM contains one V-type and one C2-type Ig domain and is involved in homophilic adhesion. Mouse ESAM extracellular domain shares 69% amino acid sequence identity with the corresponding region of human ESAM. ESAM is expressed on endothelial cells, activated platelets and megakaryocytes and can be found associated with cell-to-cell junctions.

Product Datasheets

Related Research Areas

• Adhesion Molecules in Angiogenesis
• Adhesion Molecules on Endothelial Cells
• Alpha Granule Membrane Proteins
• Endothelial Cell Markers
• Hematopoietic Stem Cell Markers
• Immunoglobulin Superfamily CAMs
• Platelet Adhesion Molecules