Mouse FoxD3 Alexa Fluor® 647-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: FoxD3

FoxD3 (forkhead box protein D3; also HNF3, HFH2 and Genesis) is a 50 kDa member of the winged helix transcription factor gene family.  It is expressed in the epiblast, migrating neural crest, and motoneurons plus interneuron progenitors of the developing spinal cord.  Mouse FoxD3 is 465 amino acids (aa) in length.  It contains a forkhead DNA binding domain (aa 131-208) plus an Ala-rich region (aa 248-464) that contains a Gly-rich motif (aa 369-399).  There appears to be one splice form that shows a four aa insert after Gly261.  Over aa 1-130, mouse FoxD3 shares 97% and 79% aa identity with rat and human FoxD3, respectively.   

Product Datasheets

Related Research Areas

• Embryonic and Induced Pluripotent Stem Cell Markers
• Forkhead Domain Transcription Factors
• Neural Crest Cell Markers
• Neural Stem Cell Markers
• Pluripotent Stem Cell Transcription Factors
• Transcription Factors and Regulators