Inducible costimulator (ICOS), also called AILIM (activation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. Human and mouse ICOS share approximately 72% amino acid sequence identity. ICOS is expressed on most CD45RO+ cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand.
Mouse ICOS (NP_059508) VersaClone cDNA
R&D Systems | Catalog # RDC0775
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: ICOS
Long Name
Inducible Co-stimulator
Alternate Names
AILIM, CD278, CRP-1
Gene Symbol
ICOS
UniProt
Additional ICOS Products
Product Documents for Mouse ICOS (NP_059508) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Mouse ICOS (NP_059508) VersaClone cDNA
For research use only
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Associated Pathways
