Mouse IL-31 Alexa Fluor® 350-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB3028U-100UG

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Mouse IL-31 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse IL-31 in direct ELISAs and Western blots. Does not cross-react with recombinant human IL‑31.
Source
Monoclonal Rat IgG2b Clone # 323407
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant mouse IL-31
Thr24-Cys163
Accession # Q6EAL8
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IL-31

IL-31 is a 25 kDa, unique member of the short chain group of alpha -helical cytokines. It is produced by activated T cells, particularly the Th2 CD4+ phenotype. Mouse IL‑31 cDNA encodes a 163 amino acid (aa) precursor that contains a 22 aa signal sequence and a 141 aa mature region. IL-31 signals through a receptor complex composed of IL-31 receptor A and Oncostatin M receptor. Mature mouse IL-31 shares 25% aa sequence identity with mature human IL-31 and 44% aa sequence identity with a rat IL-31-like protein.

Long Name
Interleukin 31
Entrez Gene IDs
386653 (Human); 76399 (Mouse)
Alternate Names
IL31; IL-31; IL-31interleukin-31; interleukin 31

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