Mouse Melanocortin-3 R/MC3R Alexa Fluor® 750-conjugated Antibody

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Mouse Melanocortin-3 R/MC3R Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Detects Melanocortin 3R/MC3R in direct ELISAs and Western blots. Stains mouse Melanocortin 3R/MC3R-transfected cells but not irrelevant transfectants.
Monoclonal Rat IgG2a Clone # 345404
Y3 rat myeloid cell line transfeced with mouse Melanocortin 3R/MC3R
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)


Recommended Concentration
Flow Cytometry
0.25-1 µg/106 cells
Mouse Melanocortin 3R/MC3R transfected HEK293 cells

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Melanocortin-3 R/MC3R

Mouse Melanocortin 3R (MC3R) is a member of the melanocortin receptor family. The 323 amino acid G-protein-coupled 7-transmembrane glycoprotein is expressed in the brain where, along with MC4R, it binds alpha, beta and gamma melanocyte stimulating hormones and is involved in regulating energy balance. MC3R is also expressed by macrophages and plays an anti-inflammatory role in the heart and other tissues. Of the 69 aa that are extracellular, mouse MC3R shares 91% and 78% sequence identity with rat and human MC3R, respectively.

Long Name
Melanocortin 3 Receptor
Entrez Gene IDs
4159 (Human); 17201 (Mouse); 29310 (Rat)
Alternate Names
BMIQ9; MC3; MC3R; MC3-R; melanocortin 3 receptor; melanocortin receptor 3; Melanocortin-3 R; Melanocortin3R; Melanocortin-3R; OB20; Obesity quantitative trait locus; OQTL

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