Melanocortin-3 R/MC3R: Products
Melanocortin-3 R (MC3R) is a G protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone. It is expressed in tissues other than the adrenal cortex and melanocytes. Mice deficient for MC3R have increased fat mass despite decreased food intake, suggesting a role in the regulation of energy homeostasis. Mutations in MC3R are associated with obesity susceptibility.