Mouse/Rat/Porcine/Canine IGF-II/IGF2 Quantikine ELISA Kit Summary
Serum-free Cell Culture Supernates, Serum, Mouse Serum, Rat Serum, Canine Serum, Porcine Serum
|Intra-Assay Precision||Inter-Assay Precision|
The recovery of IGF-II spiked to levels throughout the range of the assay in various matrices was evaluated.
|Sample Type||Average % Recovery||Range %|
|Mouse Serum (n=4)||105||86-124|
|Rat Serum (n=4)||84||78-89|
|Serum-free Cell Culture Media (n=4)||92||84-101|
Mouse/Rat/Porcine/Canine IGF-II ELISA Standard Curve
Preparation and Storage
Insulin-like growth factor (IGF)-I (also known as somatomedin C and somatomedin A) and IGF-II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved between the human, bovine and porcine proteins (100% identity), and exhibit cross-species activity.
The IGFL (insulin-like growth factor-like) family includes four small (~11 kDa), probably secreted family members in humans and one in mouse. This family shares A and B chain cysteine motifs with the IGF superfamily, and has an additional cysteine motif within an uncleaved region corresponding to the C peptide of the IGF family.
Citations for Mouse/Rat/Porcine/Canine IGF-II/IGF2 Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Critical timing of ACEi initiation prevents compensatory glomerular hypertrophy in the remaining single kidney
Authors: AS Naik, SQ Wang, M Chowdhury, J Aqeel, CL O'Connor, JE Wiggins, M Bitzer, RC Wiggins
Scientific Reports, 2021;11(1):19605.
Sample Types: Urine
Insulin-like growth factor-II overexpression accelerates parthenogenetic stem cell differentiation into cardiomyocytes and improves cardiac function after acute myocardial infarction in mice
Authors: Y Sui, W Zhang, T Tang, L Gao, T Cao, H Zhu, Q You, B Yu, T Yang
Stem Cell Res Ther, 2020;11(1):86.
Sample Types: Serum
Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling
Authors: S Chen, J Jing, Y Yuan, J Feng, X Han, Q Wen, TV Ho, C Lee, Y Chai
Cell Rep, 2020;32(6):108007.
Sample Types: Cell Culture Supernates
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