Mouse Reg3A Alexa Fluor® 488-conjugated Antibody

Catalog # Availability Size / Price Qty
AF3907G-100UG

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Mouse Reg3A Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Reg3A in direct ELISAs and Western blots. In these formats, less than 1% cross-reactivity with recombinant human Reg1B and recombinant mouse Reg1 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse Reg3A (R&D Systems, Catalog # 3907-RG)
Glu27-Gln175
Accession # O09037
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Reg3A

Regenerating islet-derived protein III alpha (Reg3A), also named Pancreatitis Associated-Protein 2 (PAP-2), is a secreted, 17 kDa member of the Reg family. These C-type lectin superfamily proteins are involved in various biological functions, including liver and pancreatic regeneration and proliferation. Reg3A is predominately expressed in intestine and exocrine pancreas. It is also induced in primary liver tumors but is not expressed in normal liver. Mature mouse Reg3A contains 149 amino acid residues and shares less than 60% aa sequence identity with other Reg3 proteins. The protein sequence of mouse Reg3A is 87% and 61% identical to that of rat and human Reg3A, respectively.

Long Name
Regenerating Islet-derived IIIa
Entrez Gene IDs
5068 (Human); 19694 (Mouse); 171162 (Rat)
Alternate Names
hepatocarcinoma-intestine-pancreas; HIPpancreatitis-associated protein; Human proislet peptide; Lithostathine 3; pancreatic beta cell growth factor; Pancreatitis-associated protein 1; PAP homologous protein; PAP1FLJ18565; PAP2; PAPPAP-H; PBCGF; proliferation-inducing protein 34; proliferation-inducing protein 42; Reg III-alpha; REG3; Reg3A; REG-3-alpha; regenerating islet-derived 3 alpha; regenerating islet-derived protein 3-alpha; Regenerating islet-derived protein III-alpha; REG-III

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