Regenerating islet-derived protein III alpha (Reg3A), also named Pancreatitis Associated-Protein 2 (PAP-2), is a secreted, 17 kDa member of the Reg family. These C-type lectin superfamily proteins are involved in various biological functions, including liver and pancreatic regeneration and proliferation. Reg3A is predominately expressed in intestine and exocrine pancreas. It is also induced in primary liver tumors but is not expressed in normal liver. Mature mouse Reg3A contains 149 amino acid residues and shares less than 60% aa sequence identity with other Reg3 proteins. The protein sequence of mouse Reg3A is 87% and 61% identical to that of rat and human Reg3A, respectively.
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Goat IgG
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Product Specifications
Immunogen
E. coli-derived recombinant mouse Reg3A (R&D Systems, Catalog # 3907-RG)
Glu27-Gln175
Accession # O09037
Glu27-Gln175
Accession # O09037
Specificity
Detects mouse Reg3A in direct ELISAs and Western blots. In these formats, less than 1% cross-reactivity with recombinant human Reg1B and recombinant mouse Reg1 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Mouse Reg3A Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Mouse Reg3A (Catalog # 3907-RG)
Sample: Recombinant Mouse Reg3A (Catalog # 3907-RG)
Reviewed Applications
Read 1 review rated 4 using AF3907 in the following applications:
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: Reg3A
Long Name
Regenerating Islet-derived IIIa
Alternate Names
Lithostathine 3, PAP2, REG3A
Gene Symbol
REG3A
UniProt
Additional Reg3A Products
Product Documents for Mouse Reg3A Antibody
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Mouse Reg3A Antibody
For research use only
Related Research Areas
Citations for Mouse Reg3A Antibody
Customer Reviews for Mouse Reg3A Antibody (1)
4 out of 5
1 Customer Rating
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Application: Western BlotSample Tested: See PMID 21410322Species: MouseVerified Customer | Posted 01/08/2015
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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