Mouse RELM beta Alexa Fluor® 350-conjugated Antibody

Catalog #: AF2730U Datasheet / COA / SDS

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AF2730U-100UG

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All RELM beta Antibodies

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Mouse RELM beta Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse RELM beta in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant rat RELM gamma is observed and 10% cross-reactivity with recombinant mouse (rm) Resistin and rmRELM alpha is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse RELMÎ²
Gly21-Ala105
Accession # Q99P86

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: RELM beta

RELM beta, also known as FIZZ2 (found in inflammatory zone 2) is a 9 kDa secreted, cysteine-rich protein belonging to the RELM family. By analogy to Resistin, RELM beta is expected to exist in two distinct multimeric structures corresponding to hexamers and trimers. RELM beta is synthesized by intestinal goblet cells and is secreted into the intestinal lumen. Mouse RELM beta shares 61% and 77% amino acid (aa) sequence identity with human and rat RELM beta, respectively. It also shares 52%, 71% and 46% aa sequence identity with mouse RELM alpha, RELM gamma and Resistin, respectively.

Long Name

Resistin-like Molecule beta

Entrez Gene IDs

84666 (Human); 57263 (Mouse)

Alternate Names

C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 2; CCRG; Colon and small intestine-specific cysteine-rich protein; Colon carcinoma-related gene protein; cysteine-rich secreted A12-alpha-like protein 1; Cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein FIZZ2; FIZZ1; FIZZ2RELM-beta; found in inflammatory zone 1; HXCP2XCP2; RELM beta; RELMb; RELMbeta; resistin like beta; resistin-like beta; RETNL2