Mouse Urotensin-II R Alexa Fluor® 647-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB9245R-025UG
FAB9245R-100UG
Detection  of Urotensin-II R in HEK293 Human Cell Line Transfected with Mouse  Urotensin-II R and eGFP by Flow Cytometry.
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Mouse Urotensin-II R Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Urotensin-II R.  Stains mouse Urotensin-II R transfectants but not irrelevant transfectants in flow cytometry.
Source
Monoclonal Rat IgG2B Clone # 443707
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse Urotensin-II R synthetic peptide
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 647

Applications

Recommended Concentration
Sample
Flow Cytometry
0.2 µg/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry Detection  of Urotensin-II R in HEK293 Human Cell Line Transfected with Mouse  Urotensin-II R and eGFP by Flow Cytometry. View Larger

Detection of Urotensin-II R in HEK293 Human Cell Line Transfected with Mouse Urotensin-II R and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) mouse Urotensin-II R or (B) irrelevant transfectants and eGFP was stained with 0.2 μg Rat Anti-Mouse Urotensin-II R Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB9245R). Quadrant markers were set based on control antibody staining (Catalog # IC013R). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: Urotensin-II R

Urotensin-II R (UR2R) belongs to the G protein-coupled receptor 1 family. UR2R is a high affinity receptor for urotensin-2 and urotensin-2B. The activity of UR2R is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. It is most abundantly expressed in the heart and pancreas. Human UR2R has been correlated with cortico-adrenal carcinoma proliferation.

Long Name
Urotensin-II Receptor
Entrez Gene IDs
2837 (Human); 217369 (Mouse); 57305 (Rat)
Alternate Names
G protein-coupled receptor 14; GPR14; G-protein coupled receptor 14; UR-2-R; UR-II-R; urotensin 2 receptor; urotensin II receptor; urotensin-2 receptor; Urotensin-II R; UrotensinIIR; Urotensin-IIR; UTR; UTR2; UTS2R

Product Datasheets

FAQs

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