Mouse Urotensin-II R Alexa Fluor® 647-conjugated Antibody Summary
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of Urotensin-II R in HEK293 Human Cell Line Transfected with Mouse Urotensin-II R and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) mouse Urotensin-II R or (B) irrelevant transfectants and eGFP was stained with 0.2 μg Rat Anti-Mouse Urotensin-II R Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB9245R). Quadrant markers were set based on control antibody staining (Catalog # IC013R). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Urotensin-II R
Urotensin-II R (UR2R) belongs to the G protein-coupled receptor 1 family. UR2R is a high affinity receptor for urotensin-2 and urotensin-2B. The activity of UR2R is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. It is most abundantly expressed in the heart and pancreas. Human UR2R has been correlated with cortico-adrenal carcinoma proliferation.
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