MRCK Antibody

Novus Biologicals | Catalog # NB300-829

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all MRCK Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence SGEVRLRQLEQFI-C corresponding to N-Terminus according to NP_003598.2.

Epitope

SGEVRLRQLEQFI-C

Specificity

This antibody is expected to recognise both reported Human isoforms (NP_055641.3 and NP_003598.2).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for MRCK Antibody

Immunohistochemistry-Paraffin: MRCK Antibody [NB300-829]

Immunohistochemistry-Paraffin: MRCK Antibody [NB300-829]

Immunohistochemistry-Paraffin: MRCK Antibody [NB300-829] - Staining of paraffin embedded Human Cerebellum. Antibody at 3.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Immunohistochemistry-Paraffin: MRCK Antibody [NB300-829]

Immunohistochemistry-Paraffin: MRCK Antibody [NB300-829]

Immunohistochemistry-Paraffin: MRCK Antibody [NB300-829] - Staining of paraffin embedded Human Small Intestine. Antibody at 3.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for MRCK Antibody

Application
Recommended Usage

Immunohistochemistry

3.75 ug/mL

Immunohistochemistry-Paraffin

3.75 ug/mL

Peptide ELISA

Detection limit 1:16000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MRCK

The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

Alternate Names

CDC42 binding protein kinase alpha (DMPK-like), CDC42 binidng protein kinase beta, CDC42-binding protein kinase alpha, CDC42-binding protein kinase alpha (DMPK-like), DMPK-like alpha, EC 2.7.11, EC 2.7.11.1, KIAA0451DKFZp686L1738, MRCK, MRCK alpha, MRCKADKFZp686P1738, Myotonic dystrophy kinase-related CDC42-binding kinase alpha, myotonic dystrophy kinase-related CDC42-binding protein kinase alpha, Myotonic dystrophy protein kinase-like alpha, PK428FLJ23347, serine/threonine-protein kinase MRCK alpha, ser-thr protein kinase PK428, ser-thr protein kinase related to the myotonic dystrophy protein kinase

Entrez Gene IDs

8476 (Human); 226751 (Mouse); 114116 (Rat)

Gene Symbol

CDC42BPA

UniProt

NP_055641 (Human)

Additional MRCK Products

Product Documents for MRCK Antibody

Certificate of Analysis

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Product Specific Notices for MRCK Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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