MSPR/Ron Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-88137

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all MSPR/Ron Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSFCPNPPGLEALSPNTSCRHFPLLVSSSF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit MSPR/Ron Antibody - BSA Free (NBP1-88137) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for MSPR/Ron Antibody - BSA Free

MSPR/Ron Antibody - BSA Free Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Staining of human cerebral cortex, gastrointestinal, lymph node and skin using Anti-MST1R antibody NBP1-88137 (A) shows similar protein distribution across tissues to independent antibody NBP1-88136 (B).
MSPR/Ron Antibody - BSA Free Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Staining of human lymph node shows no positivity in non-germinal center cells as expected.
MSPR/Ron Antibody - BSA Free Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Staining of human skin shows moderate cytoplasmic and membranous positivity in squamous epithelial cells.
MSPR/Ron Antibody - BSA Free Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Staining of human cerebral cortex shows no positivity in neurons as expected.
MSPR/Ron Antibody - BSA Free Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Immunohistochemistry-Paraffin: MSPR/Ron Antibody - BSA Free [NBP1-88137]

Staining of human rectum shows moderate cytoplasmic and membranous positivity in glandular cells.

Applications for MSPR/Ron Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MSPR/Ron

Ron, the tyrosine kinase receptor for the Macrophage-stimulating protein, is involved in cell dissociation, motility, and matrix invasion (1). Ron, a cDNA homologous to the hepatocyte growth factor (HGF) receptor gene (MET), encodes a putative tyrosine kinase. It has been shown that the Ron gene is expressed in several epithelial tissues as well as in granulocytes and monocytes. The major RON transcript is translated into a glycosylated single chain precursor, cleaved into a 185 kDa heterodimer (p185Ron) of 35 (alpha) and 150 kDa (beta) disulfide-linked chains, before exposure at the cell surface (2).

Long Name

Macrophage Stimulating Protein Receptor

Alternate Names

CD136, MSP R, MST1R, Ron

Gene Symbol

MST1R

Additional MSPR/Ron Products

Product Documents for MSPR/Ron Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for MSPR/Ron Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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