NBQX

  ( 158 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:0373
Chemical Name:2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide
Product Details
Citations (158)
Supplemental Products
Reviews
Biological Activity
Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.

Disodium Salt also available.

Technical Data
  • M.Wt:
    336.28
  • Formula:
    C12H8N4O6S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    118876-58-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Novo Nordisk A/S
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for NBQX include:

158 Citations: Showing 1 - 10
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  1. Pharmacological analysis of ionotropic glutamate receptor function in neuronal circuits of the zebrafish olfactory bulb.
    Authors: Tabor and Friedrich
    PLoS One  ;3:e1416
  2. Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice.
    Authors: Guo
    Aging Cell  2017;16(6):1323
  3. Using c-kit to genetically target cerebellar molecular layer interneurons in adult mice.
    Authors: Amat
    PLoS One  2017;12(6):e0179347
  4. Toll-like receptor 4 deficiency alters nucleus accumbens synaptic physiology and drug reward behavior.
    Authors: Kashima and Grueter
    Proc Natl Acad Sci U S A.  2017;114(33):8865
  5. Presynaptic GABAB receptors reduce transmission at parabrachial synapses in the lateral central amygdala by inhibiting N-type calcium channels.
    Authors: Delaney and Crane
    Sci Rep  2016;6:19255
  6. Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus.
    Authors: Dennis Et al.
    J Neurosci  2016;26:414
  7. Norepinephrine Modulates Pyramidal Cell Synaptic Properties in the Anterior Piriform Cortex of Mice: Age-Dependent Effects of β-adrenoceptors.
    Authors: Ghosh Et al.
    Proc Natl Acad Sci U S A  2015;9:450
  8. AMPA Receptor-mTOR Activation is Required for the Antidepressant-Like Effects of Sarcosine during the Forced Swim Test in Rats: Insertion of AMPA Receptor may Play a Role.
    Authors: Chen Et al.
    Front Behav Neurosci  2015;9:162
  9. Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice.
    Authors: Perissinotti Et al.
    Elife  2015;8:444
  10. Co-release of glutamate and GABA from single vesicles in GABAergic neurons exogenously expressing VGLUT3.
    Authors: Zimmermann Et al.
    J Neurosci  2015;7:16
  11. Optical control of NMDA receptors with a diffusible photoswitch.
    Authors: Laprell Et al.
    Front Cell Neurosci  2015;6:8076
  12. R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects.
    Authors: Yang Et al.
    Transl Psychiatry  2015;5:e632
  13. The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory.
    Authors: Marciniak Et al.
    Front Synaptic Neurosci  2015;5:15862
  14. Corelease of acetylcholine and GABA from cholinergic forebrain neurons.
    Authors: Saunders Et al.
    Cereb Cortex  2015;4
  15. A simple retinal mechanism contributes to perceptual interactions between rod- and cone-mediated responses in primates.
    Authors: Grimes Et al.
    Elife  2015;4
  16. Involvement of adrenoceptors, dopamine receptors and AMPA receptors in antidepressant-like action of 7-O-ethylfangchinoline in mice.
    Authors: Sheng Et al.
    Acta Pharmacol Sin  2015;36:949
  17. BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells.
    Authors: Hirono Et al.
    Brain Res  2015;35:7082
  18. Activation of corticostriatal circuitry relieves chronic neuropathic pain.
    Authors: Lee Et al.
    Physiol Rep  2015;35:5247
  19. Dual-channel circuit mapping reveals sensorimotor convergence in the primary motor cortex.
    Authors: Hooks Et al.
    Front Cell Neurosci  2015;35:4418
  20. Loss of Local Astrocyte Support Disrupts Action Potential Propagation and Glutamate Release Synchrony from Unmyelinated Hippocampal Axon Terminals In Vitro.
    Authors: Sobieski Et al.
    PLoS One  2015;35:11105
  21. Afterhyperpolarization (AHP) regulates the frequency and timing of action potentials in the mitral cells of the olfactory bulb: role of olfactory experience.
    Authors: Duménieu Et al.
    Sci Rep  2015;3
  22. Impact of subanesthetic doses of ketamine on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons.
    Authors: Iskandrani Et al.
    Stroke  2015;29:792
  23. Functional α7 nicotinic receptors are expressed on immature granule cells of the postnatal dentate gyrus.
    Authors: John Et al.
    J Neurosci  2015;1601:15
  24. Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture.
    Authors: Pasca Et al.
    Front Cell Neurosci  2015;12:671
  25. Tectal microcircuit generating visual selection commands on gaze-controlling neurons.
    Authors: Kardamakis Et al.
    J Neurosci  2015;112:E1956
  26. The effect of desflurane on neuronal communication at a central synapse.
    Authors: Mapelli Et al.
    Nat Commun  2015;10:e0123534
  27. HSF1 transcriptional activity mediates alcohol induction of Vamp2 expression and GABA release.
    Authors: Varodayan and Harrison
    J Neurosci  2014;7:89
  28. Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA.
    Authors: Suzuki Et al.
    Nat Commun  2014;5:4153
  29. Cross-synaptic synchrony and transmission of signal and noise across the mouse retina.
    Authors: Grimes Et al.
    Elife  2014;3:e03892
  30. Fast retrieval and autonomous regulation of single spontaneously recycling synaptic vesicles.
    Authors: Leitz and Kavalali
    Elife  2014;3:e03658
  31. Repeated binge-like ethanol drinking alters ethanol drinking patterns and depresses striatal GABAergic transmission.
    Authors: Wilcox Et al.
    Neuropsychopharmacology  2014;39:579
  32. L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner.
    Authors: Wang and Mattson
    Neurobiol Aging  2014;35:88
  33. Glycolysis and oxidative phosphorylation in neurons and astrocytes during network activity in hippocampal slices.
    Authors: Ivanov Et al.
    J Cereb Blood Flow Metab  2014;34:397
  34. A novel mechanism for nicotinic potentiation of glutamatergic synapses.
    Authors: Halff Et al.
    J Neurosci  2014;34:2051
  35. Modulation of neuronal microcircuit activities within the medial prefrontal cortex by mGluR5 positive allosteric modulator.
    Authors: Pollard Et al.
    J Psychopharmacol  2014;28:935
  36. Rac1 and rac3 GTPases control synergistically the development of cortical and hippocampal GABAergic interneurons.
    Authors: Vaghi Et al.
    Cereb Cortex  2014;24:1247
  37. CaMKII phosphorylation of neuroligin-1 regulates excitatory synapses.
    Authors: Bemben Et al.
    Nat Neurosci  2014;17:56
  38. hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice.
    Authors: Cunningham Et al.
    Cell Stem Cell  2014;15:559
  39. Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 δ glutamate receptors.
    Authors: Ady Et al.
    Proc Natl Acad Sci U S A  2014;15:103
  40. Depressed GABA and glutamate synaptic signaling by 5-HT1A receptors in the nucleus tractus solitarii and their role in cardiorespiratory function.
    Authors: Ostrowski Et al.
    J Neurophysiol  2014;111:2493
  41. Synaptic NMDA receptor-dependent Ca2+ entry drives membrane potential and Ca2+ oscillations in spinal ventral horn neurons.
    Authors: Alpert and
    PLoS One  2013;8:e63154
  42. Contribution of NMDA receptor hypofunction in prefrontal and cortical excitatory neurons to schizophrenia-like phenotypes.
    Authors: Rompala Et al.
    J Neurosci  2013;8:e61278
  43. Different transporter systems regulate extracellular GABA from vesicular and non-vesicular sources.
    Authors: Song Et al.
    Front Cell Neurosci  2013;7:23
  44. Intersecting circuits generate precisely patterned retinal waves.
    Authors: Akrouh and Kerschensteiner
    Neuron  2013;79:322
  45. Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors.
    Authors: Hamida Et al.
    Nat Neurosci  2013;33:14369
  46. Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus.
    Authors: Brady Et al.
    Proc Natl Acad Sci U S A  2013;33:1062
  47. Activity-regulated somatostatin expression reduces dendritic spine density and lowers excitatory synaptic transmission via postsynaptic somatostatin receptor 4.
    Authors: Hou and Yu
    J Biol Chem  2013;288:2501
  48. Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice.
    Authors: Ufartes Et al.
    Hum Mol Genet  2013;22:2247
  49. The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development.
    Authors: Woo Et al.
    J Cell Biol  2013;201:929
  50. Physiological release of endogenous tau is stimulated by neuronal activity.
    Authors: Pooler Et al.
    J Neuroimmunol  2013;14:389
  51. Neural progenitors organize in small-world networks to promote cell proliferation.
    Authors: Malmersjö Et al.
    J Neurosci  2013;110:E1524
  52. S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis.
    Authors: Selvakumar Et al.
    Proc Natl Acad Sci U S A  2013;110:1077
  53. AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis.
    Authors: Bonnet Et al.
    Ann Rheum Dis  2013;
  54. Axon-glia synapses are highly vulnerable to white matter injury in the developing brain.
    Authors: Shen Et al.
    J Neurosci Res  2012;90:105
  55. Differential requirement for protein synthesis in presynaptic unmuting and muting in hippocampal glutamate terminals.
    Authors: Crawford Et al.
    PLoS One  2012;7:e51930
  56. Olfactory bulb glomerular NMDA receptors mediate olfactory nerve potentiation and odor preference learning in the neonate rat.
    Authors: Lethbridge Et al.
    J Neurosci  2012;7:e35024
  57. Consolidation of remote fear memories involves Corticotropin-Releasing Hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus.
    Authors: Thoeringer Et al.
    J Neuroimmunol  2012;37:787
  58. β-Estradiol unmasks metabotropic receptor-mediated metaplasticity of NMDA receptor transmission in the female rat dentate gyrus.
    Authors: Nebieridze Et al.
    Psychoneuroendocrinology  2012;37:1845
  59. The role of inhibition in oscillatory wave dynamics in the cortex.
    Authors: Xiao Et al.
    Eur J Neurosci  2012;36:2201
  60. Mixed electrical-chemical transmission between hippocampal mossy fibers and pyramidal cells.
    Authors: Vivar Et al.
    Eur J Neurosci  2012;35:76
  61. Presynaptic Cav3.2 channels regulate excitatory neurotransmission in nociceptive dorsal horn neurons.
    Authors: Jacus Et al.
    Proc Natl Acad Sci U S A  2012;32:9374
  62. Alteration of synaptic network dynamics by the intellectual disability protein PAK3.
    Authors: Dubos Et al.
    Eur J Neurosci  2012;32:519
  63. Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals.
    Authors: Cassé Et al.
    J Neurosci  2012;32:5186
  64. Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons.
    Authors: Peterfi Et al.
    J Neurosci  2012;32:14448
  65. Lack of kinase regulation of canonical transient receptor potential 3 (TRPC3) channel-dependent currents in cerebellar Purkinje cells.
    Authors: Nelson and Glitsch
    PLoS One  2012;287:6326
  66. Essential role of brain-derived neurotrophic factor in the regulation of serotonin transmission in the basolateral amygdala.
    Authors: Daftary Et al.
    Neuroscience  2012;224:125
  67. Heterogeneous reallocation of presynaptic efficacy in recurrent excitatory circuits adapting to inactivity.
    Authors: Mitra Et al.
    Nat Neurosci  2012;15:250
  68. Focal adhesion kinase regulates actin nucleation and neuronal filopodia formation during axonal growth.
    Authors: Chacón Et al.
    Dev Neurobiol  2012;139:3200
  69. Development of NMDA NR2 subunits and their roles in critical period maturation of neocortical GABAergic interneurons.
    Authors: Zhang and Sun
    Neuropsychopharmacology  2011;71:221
  70. CDK5 is essential for soluble amyloid β-induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton.
    Authors: Roselli Et al.
    PLoS One  2011;6:e23097
  71. Synaptic responses evoked by tactile stimuli in Purkinje cells in mouse cerebellar cortex Crus II in vivo.
    Authors: Chu Et al.
    PLoS One  2011;6:e22752
  72. Cholinergic interneurons mediate fast VGluT3-dependent glutamatergic transmission in the striatum.
    Authors: Higley Et al.
    PLoS One  2011;6:e19155
  73. Sleep-deprivation regulates α-2 adrenergic responses of rat hypocretin/orexin neurons.
    Authors: Uschakov Et al.
    PLoS One  2011;6:e16672
  74. Cannabinoids attenuate hippocampal γ oscillations by suppressing excitatory synaptic input onto CA3 pyramidal neurons and fast spiking basket cells.
    Authors: Holderith Et al.
    Eur J Neurosci  2011;589:4921
  75. Calcium-independent inhibitory G-protein signaling induces persistent presynaptic muting of hippocampal synapses.
    Authors: Crawford Et al.
    Proc Natl Acad Sci U S A  2011;31:979
  76. NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination.
    Authors: Biase Et al.
    J Neurophysiol  2011;31:12650
  77. An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus.
    Authors: Etherton Et al.
    EMBO J  2011;30:2908
  78. Quantal amplitude at the cone ribbon synapse can be adjusted by changes in cytosolic glutamate.
    Authors: Bartoletti and Thoreson
    Mol Vis  2011;17:920
  79. Developmental maturation of excitation and inhibition balance in principal neurons across four layers of somatosensory cortex.
    Authors: Zhang Et al.
    J Neurosci  2011;174:45931
  80. Inflammation alters trafficking of extrasynaptic AMPA receptors in tonically firing lamina II neurons of the rat spinal dorsal horn.
    Authors: Kopach Et al.
    Pain  2011;152:912
  81. Distinct functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1.
    Authors: Straub Et al.
    Nat Neurosci  2011;14:866
  82. Ca(2+)-dependent enhancement of release by subthreshold somatic depolarization.
    Authors: Christie Et al.
    Nat Neurosci  2011;14:62
  83. The Etv1/Er81 transcription factor orchestrates activity-dependent gene regulation in the terminal maturation program of cerebellar granule cells.
    Authors: Abe Et al.
    Neuroscience  2011;108:12497
  84. Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin.
    Authors: Hossaini Et al.
    Proc Natl Acad Sci U S A  2010;6:43
  85. Facilitation of long-term potentiation by muscarinic M(1) receptors is mediated by inhibition of SK channels.
    Authors: Buchanan Et al.
    Neuron  2010;68:948
  86. Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase.
    Authors: Jackson Et al.
    PLoS One  2010;5:e11962
  87. High-Pass Filtering and Dynamic Gain Regulation Enhance Vertical Bursts Transmission along the Mossy Fiber Pathway of Cerebellum.
    Authors: Mapelli Et al.
    Proc Natl Acad Sci U S A  2010;4:14
  88. Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation.
    Authors: Mah Et al.
    J Physiol  2010;30:5559
  89. Different relationship of N- and P/Q-type Ca2+ channels to channel-interacting slots in controlling neurotransmission at cultured hippocampal synapses.
    Authors: Cao and Tsien
    J Neurosci  2010;30:4536
  90. Excitability and synaptic communication within the oligodendrocyte lineage.
    Authors: Biase Et al.
    J Neurosci  2010;30:3600
  91. Postsynaptic spiking homeostatically induces cell-autonomous regulation of inhibitory inputs via retrograde signaling.
    Authors: Peng Et al.
    J Neurosci  2010;30:16220
  92. Rapid activation of dormant presynaptic terminals by phorbol esters.
    Authors: Chang Et al.
    J Neurosci  2010;30:10048
  93. Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging.
    Authors: Potier Et al.
    Front Aging Neurosci  2010;2:1
  94. Effect of hypoxia on expiratory muscle activity in fetal sheep.
    Authors: Bissonnette Et al.
    Respir Physiol Neurobiol  2010;171:110
  95. Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors.
    Authors: Higley and Sabatini
    Nat Neurosci  2010;13:958
  96. A dynamic role for GABA receptors on the firing pattern of midbrain dopaminergic neurons.
    Authors: Lobb Et al.
    J Neurophysiol  2010;104:403
  97. Combinatorial responses controlled by synaptic inhibition in the cerebellum granular layer.
    Authors: Mapelli Et al.
    Neuropharmacology  2010;103:250
  98. Characterization of engineered channelrhodopsin variants with improved properties and kinetics.
    Authors: Lin Et al.
    Biophys J  2009;96:1803
  99. Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in Ca(v)2.1 knockin migraine mice.
    Authors: Tottene Et al.
    Neuron  2009;61:762
  100. ATP-dependent infra-slow (0.1 Hz) oscillations in thalamic networks.
    Authors: Lörincz Et al.
    PLoS One  2009;4:e4447
  101. Specific synapses develop preferentially among sister excitatory neurons in the neocortex.
    Authors: Yu Et al.
    EMBO Rep  2009;458:501
  102. NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala.
    Authors: Kenny Et al.
    Neuropsychopharmacology  2009;34:266
  103. N-methyl-D-aspartate receptor- and metabotropic glutamate receptor-dependent long-term depression are differentially regulated by the ubiquitin-proteasome system.
    Authors: Citri Et al.
    J Neurophysiol  2009;30:1443
  104. D1/D5 modulation of synaptic NMDA receptor currents.
    Authors: Varela Et al.
    J Neurosci  2009;29:3109
  105. Millisecond timescale disinhibition mediates fast information transmission through an avian basal ganglia loop.
    Authors: Leblois Et al.
    J Neurosci  2009;29:15420
  106. Chronic CXCL10 alters neuronal properties in rat hippocampal culture.
    Authors: Cho Et al.
    J Neurosci  2009;207:92
  107. AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62.
    Authors: Jiang Et al.
    Hippocampus  2009;19:392
  108. Experience-dependent intrinsic plasticity in interneurons of barrel cortex layer IV.
    Authors: Sun
    J Neurosci  2009;102:2955
  109. Co-transmission of dopamine and GABA in periglomerular cells.
    Authors: Maher and Westbrook
    J Neurophysiol  2008;99:1559
  110. GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments.
    Authors: Romo-Parra Et al.
    J Neurosci  2008;99:1523
  111. Synapse-specific adaptations to inactivity in hippocampal circuits achieve homeostatic gain control while dampening network reverberation.
    Authors: Kim and Tsien
    Neuron  2008;58:925
  112. Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test.
    Authors: Gould Et al.
    Neuropharmacology  2008;54:577
  113. Cholecystokinin inhibits endocannabinoid-sensitive hippocampal IPSPs and stimulates others.
    Authors: Karson Et al.
    J Biol Chem  2008;54:117
  114. Apoptosis induced by domoic acid in mouse cerebellar granule neurons involves activation of p38 and JNK MAP kinases.
    Authors: Giordano Et al.
    J Physiol  2008;52:1100
  115. Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development.
    Authors: Iwasato Et al.
    J Neurosci  2008;28:5931
  116. Competition between calcium-activated K+ channels determines cholinergic action on firing properties of basolateral amygdala projection neurons.
    Authors: Power and Sah
    J Neurosci  2008;28:3209
  117. White matter vulnerability to ischemic injury increases with age because of enhanced excitotoxicity.
    Authors: Baltan Et al.
    J Neurosci  2008;28:1479
  118. The chemokine CCL2 activates p38 mitogen-activated protein kinase pathway in cultured rat hippocampal cells.
    Authors: Cho and Gruol
    J Neurosci  2008;199:94
  119. Dendritic glutamate release produces autocrine activation of mGluR1 in cerebellar Purkinje cells.
    Authors: Shin Et al.
    Nature  2008;105:746
  120. Long-lasting NMDA receptor-mediated EPSCs in mouse striatal medium spiny neurons.
    Authors: Logan Et al.
    J Neurophysiol  2007;98:2693
  121. Increased thalamocortical synaptic response and decreased layer IV innervation in GAP-43 knockout mice.
    Authors: Albright Et al.
    J Neurophysiol  2007;98:1610
  122. Endogenous D-serine contributes to NMDA-receptor-mediated light-evoked responses in the vertebrate retina.
    Authors: Gustafson Et al.
    J Neurophysiol  2007;98:122
  123. Presynaptic plasma membrane Ca2+ ATPase isoform 2a regulates excitatory synaptic transmission in rat hippocampal CA3.
    Authors: Jensen Et al.
    Chem Senses  2007;579:85
  124. Long-term modifications in the strength of excitatory associative inputs in the piriform cortex.
    Authors: Young and Sun
    Proc Natl Acad Sci U S A  2007;32:783
  125. Axon and dendrite geography predict the specificity of synaptic connections in a functioning spinal cord network.
    Authors: Li Et al.
    Neural Dev  2007;2:17
  126. Plasma membrane Ca2+ ATPase 2 contributes to short-term synapse plasticity at the parallel fiber to Purkinje neuron synapse.
    Authors: Empson Et al.
    Proc Natl Acad Sci U S A  2007;27:3753
  127. Disynaptic amplification of metabotropic glutamate receptor 1 responses in the olfactory bulb.
    Authors: Jan and Westbrook
    J Neurosci  2007;27:132
  128. Somatodendritic release of glutamate regulates synaptic inhibition in cerebellar Purkinje cells via autocrine mGluR1 activation.
    Authors: Duguid Et al.
    J Neurosci  2007;27:12464
  129. Potent and specific action of the mGlu1 antagonists YM-298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices.
    Authors: Fukunaga Et al.
    Br J Pharmacol  2007;151:870
  130. Vesicular release of glutamate from unmyelinated axons in white matter.
    Authors: Ziskin Et al.
    Front Integr Neurosci  2007;10:321
  131. Properties of GluR3 receptors tagged with GFP at the amino or carboxyl terminus.
    Authors: Limon Et al.
    Proc Natl Acad Sci U S A  2007;104:15526
  132. Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency.
    Authors: Giordano Et al.
    Mol Pharmacol  2006;70:2116
  133. Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability.
    Authors: Jakubs Et al.
    Neuron  2006;52:1047
  134. Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking.
    Authors: Bäckström and Hyytiä
    Neuropsychopharmacology  2006;31:778
  135. Glial glutamate transporters maintain one-to-one relationship at the climbing fiber-Purkinje cell synapse by preventing glutamate spillover.
    Authors: Takayasu Et al.
    J Neurosci  2006;26:6563
  136. Regulated expression of HCN channels and cAMP levels shape the properties of the h current in developing rat hippocampus.
    Authors: Surges Et al.
    Mol Pain  2006;24:94
  137. Adaptation to synaptic inactivity in hippocampal neurons.
    Authors: Thiagarajan Et al.
    Neuron  2005;47:725
  138. Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation.
    Authors: Weitlauf Et al.
    Neurochem Int  2005;25:8386
  139. Programmed and induced phenotype of the hippocampal granule cells.
    Authors: Gómez-Lira Et al.
    J Neurosci  2005;25:6939
  140. Calcium increases in retinal glial cells evoked by light-induced neuronal activity.
    Authors: Newman
    Nat Methods  2005;25:5502
  141. Differences in transmission properties and susceptibility to long-term depression reveal functional specialization of ascending axon and parallel fiber synapses to Purkinje cells.
    Authors: Sims and Hartell
    EMBO Rep  2005;25:3246
  142. Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons.
    Authors: Calò Et al.
    J Neurosci  2005;25:2245
  143. Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1.
    Authors: Rhee Et al.
    J Neurosci  2005;102:18664
  144. Endocannabinoid-mediated metaplasticity in the hippocampus.
    Authors: Chevaleyre and Castillo
    Neuron  2004;43:871
  145. Glucose but not lactate in combination with acidosis aggravates ischemic neuronal death in vitro.
    Authors: Cronberg Et al.
    Proc Natl Acad Sci U S A  2004;35:753
  146. Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis.
    Authors: Tongiorgi Et al.
    Development  2004;24:6842
  147. Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons.
    Authors: Huang Et al.
    J Neurosci  2004;24:4551
  148. Functional excitatory synapses in HEK293 cells expressing neuroligin and glutamate receptors.
    Authors: Fu Et al.
    J Neurophysiol  2003;90:3950
  149. Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism.
    Authors: Paladini Et al.
    Proc Natl Acad Sci U S A  2003;100:2866
  150. A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses.
    Authors: Yamaguchi Et al.
    J Neurophysiol  2002;99:14536
  151. The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders.
    Authors: Andrieux Et al.
    Genes Dev  2002;16:2350
  152. Glutamate antagonists limit tumor growth.
    Authors: Rzeski Et al.
    Proc Natl Acad Sci U S A  2001;98:6372
  153. Kainate receptor-mediated synaptic currents in cerebellar Golgi cells are not shaped by diffusion of glutamate.
    Authors: Bureau Et al.
    Proc Natl Acad Sci U S A  2000;97:6838
  154. Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse.
    Authors: Casado Et al.
    J Neurosci  2000;97:11593
  155. Histamine depolarizes cholinergic interneurones in the rat striatum via a H(1)-receptor mediated action.
    Authors: Bell Et al.
    Br J Pharmacol  2000;131:1135
  156. Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of back-propagating action potentials and subthreshold excitatory postsynaptic potentials.
    Authors: Koester and Sakmann
    PLoS One  1998;95:9596
  157. Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2.
    Authors: Miettinen Et al.
    J Psychopharmacol  1997;94:6500
  158. Effect of chronic ethanol treatment in vivo on excitability in mouse cortical neurones in vitro.
    Authors: Ibbotson Et al.
    Br J Pharmacol  1997;122:956
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Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

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