NBQX disodium salt

  ( 17 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:1044
Chemical Name:2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt
Product Details
Citations (17)
Supplemental Products
Reviews
Biological Activity
Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo. More water soluble disodium salt of NBQX (Cat. No. 0373). Also available as part of the AMPA Receptor Tocriset™.
Technical Data
  • M.Wt:
    380.24
  • Formula:
    C12H6N4O6SNa2
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    479347-86-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Novo Nordisk A/S
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for NBQX disodium salt include:

17 Citations: Showing 1 - 10
Filter your results:

  1. Basolateral amygdala rapid glutamate release encodes an outcome-specific representation vital for reward-predictive cues to selectively invigorate reward-seeking actions.
    Authors: Malvaez Et al.
    PLoS One  2015;5:12511
  2. Muscarinic receptors modulate dendrodendritic inhibitory synapses to sculpt glomerular output.
    Authors: Liu Et al.
    Sci Rep  2015;35:5680
  3. Milnacipran remediates impulsive deficits in rats with lesions of the ventromedial prefrontal cortex.
    Authors: Tsutsui-Kimura Et al.
    Neuron  2015;18
  4. Pharmacological Investigation of Fluoro-Gold Entry into Spinal Neurons.
    Authors: Falgairolle and O'Donovan
    Neurochem Int  2015;10:e0131430
  5. Step-by-step instructions for retina recordings with perforated multi electrode arrays.
    Authors: Reinhard Et al.
    PLoS One  2014;9:e106148
  6. Translaminar inhibitory cells recruited by layer 6 corticothalamic neurons suppress visual cortex.
    Authors: Bortone Et al.
    J Neurosci  2014;82:474
  7. A synaptic signature for ON- and OFF-center parasol ganglion cells of the primate retina.
    Authors: Crook Et al.
    Vis Neurosci  2014;31:57
  8. The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition.
    Authors: Bloodgood Et al.
    Nature  2013;503:121
  9. Synaptic and extrasynaptic plasticity in glutamatergic circuits involving dentate granule cells following chronic N-methyl-D-aspartate receptor inhibition.
    Authors: He Et al.
    Int J Neuropsychopharmacol  2013;109:1535
  10. Topiramate treatment is neuroprotective and reduces oligodendrocyte loss after cervical spinal cord injury.
    Authors: Gensel Et al.
    J Neurosci  2012;7:e33519
  11. Gain control by layer six in cortical circuits of vision.
    Authors: Olsen Et al.
    J Neurophysiol  2012;483:47
  12. Pharmacological evidence that D-aspartate activates a current distinct from ionotropic glutamate receptor currents in Aplysia californica.
    Authors: Carlson Et al.
    Brain Behav  2012;2:391
  13. Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity.
    Authors: Butti Et al.
    Brain  2012;135:3320
  14. SAP102 is a highly mobile MAGUK in spines.
    Authors: Zheng Et al.
    J Neurosci  2010;30:4757
  15. Vasoconstrictive neurovascular coupling during focal ischemic depolarizations.
    Authors: Shin Et al.
    J Cereb Blood Flow Metab  2006;26:1018
  16. Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3.
    Authors: Harkany Et al.
    PLoS One  2004;24:4978
  17. Astrocyte-mediated activation of neuronal kainate receptors.
    Authors: Liu Et al.
    Nature  2004;101:3172
Expand to show all Citations

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs
Average Rating: 5 (Based on 1 review)

Have you used NBQX disodium salt?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Read what people are saying who have used NBQX disodium salt.

We have 1 review tested in 1 species: Mouse.

Filter by Ratings
Excellent
(1)
All Ratings
Filter by Applications
All Applications
Filter by Species
Mouse
(1)
All Species

Images Ratings Applications Species Reviewed By Date Details
  Excellent
  Mouse Andy Gao 01/13/2018
Show

Summary

Species Mouse

Other Experimental Details

Other Experimental Details Aliquot properly in dMSO

Please scroll the above reviews for more
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
You May Also Like
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee