Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free

Novus Biologicals | Catalog # NBP2-79847

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG Clone # NRG1/2752

Format

Azide and BSA Free
View all Neuregulin-1/NRG1 Primary Antibodies »

Product Specifications

Immunogen

Recombinant fragment of human Neuregulin-1/NRG1 protein (around aa 21-242) (exact sequence is proprietary) (Uniprot: Q02297)

Localization

Cell Surface, Cytoplasmic (Secreted)

Marker

Breast and Urothelial Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Description

1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP2-79713).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free

Immunocytochemistry/ Immunofluorescence: Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free [NBP2-79847]

Immunocytochemistry/ Immunofluorescence: Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free [NBP2-79847]

Immunocytochemistry/Immunofluorescence: Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free [NBP2-79847] - Confocal immunofluorescence of PFA-fixed MCF-7 cells using Neuregulin-1/NRG1 Antibody (NRG1/2752) followed by Goat-anti Mouse CF488 (green) and RedDot is used to label the nuclei red.
Protein Array: Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free [NBP2-79847]

Protein Array: Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free [NBP2-79847]

Protein Array: Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free [NBP2-79847] - Analysis of Protein Array containing more than 19,000 full-length human proteins using Neuregulin-1/NRG1 Antibody (NRG1/2752). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combinatio

Applications for Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1-2 ug/ml
Application Notes
ELISA: For coating, order Ab without BSA.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: Neuregulin-1/NRG1

Neuregulin 1 (NRG1, isoform HRG-beta2) belongs to the neuregulin/heregulin cytokine family consisting of variants of the four genes NRG1, NRG2, NRG3 and NRG4. More than 15 transmembrane and secreted protein isoforms exist for NRG1, they are generated by alternative promoter usage and mRNA splicing. The different isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. The EGF-like domain interacts with ErbB3 and ErbB4 tyrosine kinase receptors, resulting in tyrosine phosphorylation and NRG1 signaling. NRG proteins show distinct spatial and temporal expression patterns. These proteins are important for the development of the nervous system and the heart and in the regulation of neurotransmission.

Alternate Names

Heregulin-1, HGL, HRG1-alpha, HRG1-beta 1, Neuregulin1, NRG1

Gene Symbol

NRG1

Additional Neuregulin-1/NRG1 Products

Product Documents for Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for Neuregulin-1/NRG1 Antibody (NRG1/2752) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

EGF Family
Neuronal Lineage Markers

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Protocols

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FAQs

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