NOD1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-76286

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Rat

Applications

Validated:

Western Blot, ELISA, Flow Cytometry

Cited:

Flow Cytometry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all NOD1 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the carboxy end of human NOD1. The immunogen is located within the last 50 amino acids of NOD1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NOD1 Antibody - BSA Free

Western Blot: NOD1 AntibodyBSA Free [NBP1-76286]

Western Blot: NOD1 AntibodyBSA Free [NBP1-76286]

Western Blot: NOD1 Antibody [NBP1-76286] - EL4 cell lysate with NOD1 antibody at 1 ug/mL.

Applications for NOD1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

Reported in scientific literature (PMID 27747243)

Western Blot

1 ug/ml

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NOD1

NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-kappaB. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

Long Name

Nucleotide-binding Oligomerization Domain-containing Protein 1

Alternate Names

CARD4, CLR7.1, NLRC1

Gene Symbol

NOD1

Additional NOD1 Products

Product Documents for NOD1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for NOD1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for NOD1 Antibody - BSA Free

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Protocols

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FAQs

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Associated Pathways

NOD-like Receptor Signaling Pathways NOD-like Receptor Signaling Pathway Thumbnail