Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Noggin Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide comprising an internal sequence of the human Noggin protein. Sequence is 100% conserved in rat and mouse (NP_005441).

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat

Specificity

Noggin

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

25.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Noggin Antibody - BSA Free

Western Blot: Noggin AntibodyBSA Free [NB100-93547]

Western Blot: Noggin AntibodyBSA Free [NB100-93547]

Western Blot: Noggin Antibody [NB100-93547] 20ug of human hippocampus tissue lysate (lanes 2 and 4) with Noggin polyclonal at 1:1000 dilution followed by secondary at 1:5000 dilution MW marker Lane 1 peptide absorption control lane 3.

Applications for Noggin Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:1000-1:2000
Application Notes
This antibody is useful for Western Blot 1:1000-1:2000. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Noggin

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Alternate Names

NOG, SYM1, SYNS1, SYNS1A

Entrez Gene IDs

9241 (Human); 18121 (Mouse); 25495 (Rat)

Gene Symbol

NOG

UniProt

Q13253

Additional Noggin Products

Product Documents for Noggin Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Noggin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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