Numb Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-30927

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free
View all Numb Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide derived from human Numb protein

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Numb Antibody - BSA Free

Numb Antibody

Western Blot: Numb Antibody [NBP3-30927] -

Western Blot: Numb Antibody [NBP3-30927] - Western blot using anti-Numb antibody (Cat. No. NBP3-30927) on human brain lysate (14ug/lane). Antibody was used with (lane 1) and without (lane 2) blocking peptide at 10ug/ml.

Applications for Numb Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

: 10-15 ug/ml

Western Blot

: 1:400
Application Notes
.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Phosphate buffered saline

Format

BSA Free

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Numb

Numb is a transmembrane signaling receptor that is activated by the DSL family of ligands. Studies suggestthat mammalian Numb plays a role in progenitor cell fate in neurogenesis. Numb exerts its role on cell fate by antagonizing Notch signaling. The mammalian Numb gene undergoes alternative splicing to produce at least four functionally different Numb isoforms which regulate different processes. A loss of Numb expression has been demonstrated in breast cancer, non-small cell lung cancer and chronic myelogenous leukemia.

Alternate Names

m-numb, mnb, S171

Gene Symbol

NUMB

Additional Numb Products

Product Documents for Numb Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Numb Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Neural Crest Cell Markers
Notch Pathway

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

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Associated Pathways

Notch Signaling Pathways Notch Signaling Pathway Thumbnail