NUP214 Antibody

Name: NUP214 Antibody
Brand: Novus Biologicals
SKU: NB100-2245
Price: 459 USD
Availability: InStock

Novus Biologicals | Catalog # NB100-2245

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human, Mouse

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 2050 and the C-terminus (residue 2090) of human Nuceloporin 214 using the numbering given in entry NP_005076.3 (GeneID 8021).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NUP214 Antibody

Western Blot: NUP214 Antibody [NB100-2245]

Western Blot: NUP214 Antibody [NB100-2245] - Detection of Human and Mouse NUP214 on HeLa whole cell lysate using NB100-2245. NUP214 was also immunoprecipitated using rabbit anti-NUP214 antibody NB100-2244.

Applications for NUP214 Antibody

Application

Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: NUP214

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome.

Alternate Names

214 kDa nucleoporin, CAINputative oncogene, D9S46Enuclear pore complex protein Nup214, KIAA0023, MGC104525, N214, nucleoporin 214kD (CAIN), nucleoporin 214kDa, Nucleoporin Nup214, p250, Protein CAN

Entrez Gene IDs

8021 (Human); 227720 (Mouse)

Gene Symbol

NUP214

UniProt

P35658 (Human)

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Product Documents for NUP214 Antibody

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Certificate of Analysis

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Product Specific Notices for NUP214 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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